The current status of neutrophil cytoplasmic antibodies

Several studies in the past 10 years have demonstrated the occurrence of autoantibodies against cytoplasmic constituents in patients with vasculitis and glomerulonephritis. In this review the nomenclature of these antibodies is discussed and assays and clinical associations are summarized. Although...

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Hauptverfasser: Woude, Fokko J. van der (VerfasserIn) , Daha, Mohamed R. (VerfasserIn) , Es, Leendert Adriaan van (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 1989
In: Clinical & experimental immunology
Year: 1989, Jahrgang: 78, Heft: 2, Pages: 143-148
ISSN:1365-2249
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1534659
Volltext
Verfasserangaben:F.J. van der Woude, M.R. Daha & L.A. van Es

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520 |a Several studies in the past 10 years have demonstrated the occurrence of autoantibodies against cytoplasmic constituents in patients with vasculitis and glomerulonephritis. In this review the nomenclature of these antibodies is discussed and assays and clinical associations are summarized. Although the antigens involved are not completely identified, antibodies and T cells reactive with myeloid lysozomal enzymes may both play a significant role in pathogenesis. 
650 4 |a Antibodies, Antineutrophil Cytoplasmic 
650 4 |a Autoantigens 
650 4 |a Glomerulonephritis 
650 4 |a Humans 
650 4 |a Immunoassay 
650 4 |a Models, Immunological 
650 4 |a Terminology as Topic 
650 4 |a Vasculitis 
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