Distinct types of tumor-initiating cells form human colon cancer tumors and metastases

Human colon cancer harbors a small subfraction of tumor-initiating cells (TICs) that is assumed to be a functionally homogeneous stem-cell-like population driving tumor maintenance and metastasis formation. We found unexpected cellular heterogeneity within the TIC compartment, which contains three t...

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Bibliographic Details

Main Authors:	Dieter, Sebastian M. (Author) , Ball, Claudia R. (Author) , Hoffmann, Christopher M. (Author) , Nowrouzi, Ali (Author) , Herbst, Friederike (Author) , Zavidij, Oksana (Author) , Abel, Ulrich (Author) , Arens, Anne (Author) , Weichert, Wilko (Author) , Brand, Karsten (Author) , Koch, Moritz (Author) , Weitz, Jürgen (Author) , Schmidt, Manfred (Author) , Kalle, Christof von (Author) , Glimm, Hanno (Author)
Format:	Article (Journal)
Language:	English
Published:	October 7, 2011
In:	Cell stem cell Year: 2011, Volume: 9, Issue: 4, Pages: 357-365
ISSN:	1875-9777
DOI:	10.1016/j.stem.2011.08.010
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.stem.2011.08.010 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1934590911003912
Author Notes:	Sebastian M. Dieter, Claudia R. Ball, Christopher M. Hoffmann, Ali Nowrouzi, Friederike Herbst, Oksana Zavidij, Ulrich Abel, Anne Arens, Wilko Weichert, Karsten Brand, Moritz Koch, Jürgen Weitz, Manfred Schmidt, Christof von Kalle, and Hanno Glimm