Targets for endothelin in the diseased kidney: clues for therapeutic intervention

The endothelin system has been implicated in various renal diseases. This review focuses on the involvement of endothelin-1 in pathogenesis and pathophysiology of acute and chronic renal failure with regard to its hemodynamic and nonhemodynamic effects. Future developments concerning the use of endo...

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Bibliographic Details
Main Authors: Rohmeiss, Peter (Author) , Birck, Rainer (Author) , Braun, Claude (Author) , Kirchengast, Michael (Author) , Woude, Fokko J. van der (Author)
Format: Article (Journal)
Language:English
Published: 1999
In: Nephron
Year: 1999, Volume: 7, Issue: 1, Pages: 1-10
ISSN:1423-0186
DOI:10.1159/000020577
Online Access:Verlag, lizenzpflichtig, Volltext: https://dx.doi.org/10.1159/000020577
Verlag, lizenzpflichtig, Volltext: https://www.karger.com/Article/FullText/20577
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Author Notes:P. Rohmeiss, R. Birck, C. Braun, M. Kirchengast, F.J. van der Woude
Description
Summary:The endothelin system has been implicated in various renal diseases. This review focuses on the involvement of endothelin-1 in pathogenesis and pathophysiology of acute and chronic renal failure with regard to its hemodynamic and nonhemodynamic effects. Future developments concerning the use of endothelin receptor antagonists and the role of endothelin in the kidney transplantation setting are discussed.
Item Description:Gesehen am 17.06.2022
Physical Description:Online Resource
ISSN:1423-0186
DOI:10.1159/000020577