Targets for endothelin in the diseased kidney: clues for therapeutic intervention

The endothelin system has been implicated in various renal diseases. This review focuses on the involvement of endothelin-1 in pathogenesis and pathophysiology of acute and chronic renal failure with regard to its hemodynamic and nonhemodynamic effects. Future developments concerning the use of endo...

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Hauptverfasser: Rohmeiss, Peter (VerfasserIn) , Birck, Rainer (VerfasserIn) , Braun, Claude (VerfasserIn) , Kirchengast, Michael (VerfasserIn) , Woude, Fokko J. van der (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 1999
In: Nephron
Year: 1999, Jahrgang: 7, Heft: 1, Pages: 1-10
ISSN:1423-0186
DOI:10.1159/000020577
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://dx.doi.org/10.1159/000020577
Verlag, lizenzpflichtig, Volltext: https://www.karger.com/Article/FullText/20577
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Verfasserangaben:P. Rohmeiss, R. Birck, C. Braun, M. Kirchengast, F.J. van der Woude
Beschreibung
Zusammenfassung:The endothelin system has been implicated in various renal diseases. This review focuses on the involvement of endothelin-1 in pathogenesis and pathophysiology of acute and chronic renal failure with regard to its hemodynamic and nonhemodynamic effects. Future developments concerning the use of endothelin receptor antagonists and the role of endothelin in the kidney transplantation setting are discussed.
Beschreibung:Gesehen am 17.06.2022
Beschreibung:Online Resource
ISSN:1423-0186
DOI:10.1159/000020577