PDGF-BB induces expression of LTBP-1 but not TGF-β1 in a rat cirrhotic fat storing cell line
TGF-β, a profibrogenic cytokine is predominantly secreted as a latent molecule complexed with one of the latent TGF-β binding proteins (LTBP). Due to the proposed functions of LTBP-1 and -3 in regulating TGF-β-bioavailability and -activity, we investigated the effects of PDGF-BB and TGF-β1 on their...
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| Main Authors: | , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2003
|
| In: |
Growth factors
Year: 2003, Volume: 21, Issue: 3/4, Pages: 121-130 |
| ISSN: | 1029-2292 |
| DOI: | 10.1080/08977190310001637224 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1080/08977190310001637224 |
| Author Notes: | Jens H. Westhoff, Iris Sawitza, Jorma Keski-Oja, Axel M. Gressner & Katja Breitkopf |
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