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Characterization of intracellular pathways leading to coinduction of thrombospondin-1 and TGF-β1 expression in rat hepatic stellate cells

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Accumulating evidence has identified Thrombospondin (TSP)-1 as important activator of latent TGF-β. Since little is known about signal transduction pathways regulating TSP expression in liver, we investigated cytokine-mediated upregulation of TSP-1 and TGF-β1 in primary rat hepatic stellate cells (H...

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Main Authors: Breitkopf-Heinlein, Katja (Author) , Sawitza, Iris (Author) , Gressner, Axel M. (Author)
Format: Article (Journal)
Language:English
Published: 2005
In: Growth factors
Year: 2005, Volume: 23, Issue: 2, Pages: 77-85
ISSN:1029-2292
DOI:10.1080/08977190500095980
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1080/08977190500095980
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Author Notes:Katja Breitkopf, Iris Sawitza & Axel M. Gressner
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PDGF-BB induces expression of LTBP-1 but not TGF-β1 in a rat cirrhotic fat storing cell line by Westhoff, Jens (Author) , Sawitza, Iris (Author) , Keski-Oja, Jorma (Author) , Gressner, Axel M. (Author) , Breitkopf-Heinlein, Katja (Author) ,


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