Return to work, fatigue and cancer rehabilitation after curative radiotherapy and radiochemotherapy for pelvic gynecologic cancer
Pain, fatigue, and depression are a common cluster of symptoms among cancer patients that impair quality of life and daily activities. We aimed to evaluate the burden of cancer rehabilitation and return-to-work (RTW) rates. Tumor characteristics, lifestyle and household details, treatment data, the...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
8 May 2022
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| In: |
Cancers
Year: 2022, Volume: 14, Issue: 9, Pages: 1-14 |
| ISSN: | 2072-6694 |
| DOI: | 10.3390/cancers14092330 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/cancers14092330 Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2072-6694/14/9/2330 |
| Author Notes: | Eva Meixner, Elisabetta Sandrini, Line Hoeltgen, Tanja Eichkorn, Philipp Hoegen, Laila König, Nathalie Arians, Jonathan W. Lischalk, Markus Wallwiener, Ilse Weis, Daniela Roob, Jürgen Debus and Juliane Hörner-Rieber |
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| 520 | |a Pain, fatigue, and depression are a common cluster of symptoms among cancer patients that impair quality of life and daily activities. We aimed to evaluate the burden of cancer rehabilitation and return-to-work (RTW) rates. Tumor characteristics, lifestyle and household details, treatment data, the use of in-house social services and post-treatment inpatient rehabilitation, and RTW were assessed for 424 women, diagnosed with cervical, uterine, or vaginal/vulvar cancer, receiving curative radio(chemo)therapy. Progression-free RTW rate at 3 months was 32.3%, and increased to 58.1% and 63.2% at 12 and 18 months, respectively. Patients with advanced FIGO stages and intensified treatments significantly suffered more from acute pain and fatigue. A higher Charlson-Comorbidity-Index reliably predicted patients associated with a higher risk of acute fatigue during RT. Aside from the presence of children, no other household or lifestyle factor was correlated with increased fatigue rates. Women aged ≤ 45 years had a significantly higher risk of developing depression requiring treatment during follow-up. Post-treatment inpatient cancer rehabilitation, including exercise and nutrition counseling, significantly relieved fatigue symptoms. The burdens for recovery from cancer therapy remain multi-factorial. Special focus needs to be placed on identifying high-risk groups experiencing fatigue or pain. Specialized post-treatment inpatient cancer rehabilitation can improve RTW rates. | ||
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