Dual-layer spectral CTA for TAVI planning using a split-phase protocol and low-keV virtual monoenergetic images: improved image quality in comparison with single-phase conventional CTA

Purpose: Adaptation of computed tomography protocols for transcatheter aortic valve implantation (TAVI) planning is required when a first-generation dual-layer spectral CT scanner (DLCT) is used. The purpose of this study was to evaluate the objective image quality of aortic CT angiography (CTA) for...

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Main Authors: Mangold, David Lukas (Author) , Salatzki, Janek (Author) , Riffel, Johannes (Author) , Kauczor, Hans-Ulrich (Author) , Weber, Tim (Author)
Format: Article (Journal)
Language:English
Published: 2022
In: RöFo
Year: 2022, Volume: 194, Issue: 6, Pages: 652-659
ISSN:1438-9010
DOI:10.1055/a-1717-2542
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1055/a-1717-2542
Verlag, lizenzpflichtig, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/a-1717-2542
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Author Notes:David Mangold, Janek Salatzki, Johannes Riffel, Hans-Ulrich Kauczor, Tim Frederik Weber

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246 1 |i Deutsche Zusammenfassung unter dem Titel  |a Verbesserte Bildqualität der TAVI-CTA eines Dual-Layer Spektral-CTs unter Verwendung eines Zwei-Phasen-Protokolls und virtuell-monoenergetischer Bilder im Vergleich zu einem konventionellen CT 
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500 |a First published online: 28. Dezember 2021 
500 |a Gesehen am 29.06.2022 
520 |a Purpose: Adaptation of computed tomography protocols for transcatheter aortic valve implantation (TAVI) planning is required when a first-generation dual-layer spectral CT scanner (DLCT) is used. The purpose of this study was to evaluate the objective image quality of aortic CT angiography (CTA) for TAVI planning using a split-phase technique with reconstruction of 40 keV virtual monoenergetic images (40 keV-VMI) obtained with a DLCT scanner. CT angiography obtained with a single-phase protocol of a conventional single-detector CT (SLCT) was used for comparison. Materials and Methods: 75 CTA scans from DLCT were retrospectively compared to 75 CTA scans from SLCT. For DLCT, spiral CTA without ECG-synchronization was performed immediately after a retrospectively ECG-gated acquisition covering the heart and aortic arch. For SLCT, spiral CTA with retrospective ECG-gating was performed to capture the heart and the access route simultaneously in one scan. Objective image quality was compared at different levels of the arterial access route. Results : 40 keV virtual monoenergetic images of DLCT showed a significantly higher mean vessel attenuation, SNR, and CNR at all levels of the arterial access route. With 40 keV-VMI of DLCT, the overall mean aortic attenuation of all six measured regions was 589.6 ± 243 HU compared to 492.7 ± 209 HU of SLCT (p < 0.01). A similar trend could be observed for SNR (23.6 ± 18 vs. 18.6 ± 9; p < 0.01) and CNR (21.1 ± 18 vs. 16.4 ± 8; p < 0.01). No deterioration was observed for vascular noise (27.8 ± 9 HU vs. 28.1 ± 8 HU; p = 0.599). Conclusion: Using a DLCT scanner with a split-phase protocol and 40 keV-VMI for TAVI planning, higher objective image quality can be obtained compared to a single-phase protocol of a conventional CT scanner. 
546 |a Text auf Englisch, Zusammenfassung auf Deutsch und Englisch 
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