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Inhibition of LPS-induced chemokine production in human lung endothelial cells by lipid conjugates anchored to the membrane

In acute respiratory distress syndrome (ARDS) induced by endotoxins, a high production of inflammatory mediators by microvascular lung endothelial cells (LMVEC) can be observed. Activation of cells by endotoxins may result in elevated secretion of phospholipase A2 (sPLA2) which is thought to contrib...

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Main Authors: Beck, Grietje (Author) , Yard, Benito A. (Author) , Schulte, Jutta (Author) , Oberacker, Ralph (Author) , Ackern, Klaus van (Author) , Woude, Fokko J. van der (Author) , Krimsky, M (Author) , Kaszkin, M (Author) , Yedgar, S (Author)
Format: Article (Journal)
Language:English
Published: 2002
In: British journal of pharmacology
Year: 2002, Volume: 135, Issue: 7, Pages: 1665-1674
ISSN:1476-5381
DOI:10.1038/sj.bjp.0704618
Online Access:Verlag, lizenzpflichtig, Volltext: https://dx.doi.org/10.1038/sj.bjp.0704618
Verlag, lizenzpflichtig, Volltext: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573284/
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Author Notes:G Ch Beck, B A Yard, J Schulte, R Oberacker, K van Ackern, F J van der Woude, M Krimsky, M Kaszkin & S Yedgar

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