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Increased expression of OLFM4 and lysozyme during necrotizing enterocolitis in neonates: an observational research study

In neonatal patients with necrotizing enterocolitis (NEC) the inflammatory response is mediated by a plurality of different proteins. The proteins olfactomedin 4 (OLFM4) and lysozyme (LYZ) are part of the intestinal mucosal defense and especially OLFM4 has rarely been evaluated in neonatal gastroint...

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Hauptverfasser: Diez, Sonja (VerfasserIn) , Renner, Marcus (VerfasserIn) , Bahlinger, Veronika (VerfasserIn) , Hartmann, Arndt (VerfasserIn) , Besendörfer, Manuel (VerfasserIn) , Müller, Hannah (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 11 April 2022
In: BMC pediatrics
Year: 2022, Jahrgang: 22, Heft: 1, Pages: 1-9
ISSN:1471-2431
DOI:10.1186/s12887-022-03260-y
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12887-022-03260-y
Volltext
Verfasserangaben:Sonja Diez, Marcus Renner, Veronika Bahlinger, Arndt Hartmann, Manuel Besendörfer and Hanna Müller
Beschreibung
Zusammenfassung:In neonatal patients with necrotizing enterocolitis (NEC) the inflammatory response is mediated by a plurality of different proteins. The proteins olfactomedin 4 (OLFM4) and lysozyme (LYZ) are part of the intestinal mucosal defense and especially OLFM4 has rarely been evaluated in neonatal gastrointestinal diseases. The aim of this study was to analyze whether expression levels of both proteins of innate immunity, OLFM4 and lysozyme, were increased during NEC in neonates.
Beschreibung:Gesehen am 06.07.2022
Beschreibung:Online Resource
ISSN:1471-2431
DOI:10.1186/s12887-022-03260-y

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