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Functional analysis of bispecific antibody (EpCAMxCD3)-mediated T-lymphocyte and cancer cell interaction by single-cell force spectroscopy

The atomic force microscopy (AFM) is a powerful tool to analyze forces generated on cellular interactions on the single-cell level. This highly sensitive device can record changes in force in the pico-Newton range, which equals single molecule bonds. Here, we have used single-cell force spectroscopy...

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Main Authors: Hoffmann, Sabrina (Author) , Wabnitz, Guido H. (Author) , Samstag, Yvonne (Author) , Moldenhauer, Gerhard (Author) , Ludwig, Thomas (Author)
Format: Article (Journal)
Language:English
Published: [1 May 2011]
In: International journal of cancer
Year: 2011, Volume: 128, Issue: 9, Pages: 2096-2104
ISSN:1097-0215
DOI:10.1002/ijc.25556
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/ijc.25556
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.25556
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Author Notes:Sabrina C. Hoffmann, Guido H. Wabnitz, Yvonne Samstag, Gerhard Moldenhauer and Thomas Ludwig

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