Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia

The aberrant accumulation of lipids in the liver (“fatty liver”) is tightly associated with several components of the metabolic syndrome, including type 2 diabetes, coronary heart disease, and atherosclerosis. Here we show that the impaired hepatic expression of transcriptional cofactor transducin b...

Full description

Saved in:
Bibliographic Details
Main Authors: Kulozik, Philipp (Author) , Jones, Allan (Author) , Mattijssen, Frits (Author) , Rose, Adam J. (Author) , Reimann, Anja (Author) , Strzoda, Daniela (Author) , Kleinsorg, Stefan (Author) , Raupp, Christina (Author) , Kleinschmidt, Jürgen (Author) , Müller-Decker, Karin (Author) , Wahli, Walter (Author) , Sticht, Carsten (Author) , Gretz, Norbert (Author) , von Loeffelholz, Christian (Author) , Stockmann, Martin (Author) , Pfeiffer, Andreas (Author) , Stöhr, Sigrid (Author) , Dallinga-Thie, Geesje M. (Author) , Nawroth, Peter Paul (Author) , Berriel Diaz, Mauricio (Author) , Herzig, Stephan (Author)
Format: Article (Journal)
Language:English
Published: 5 April 2011
In: Cell metabolism
Year: 2011, Volume: 13, Issue: 4, Pages: 389-400
ISSN:1932-7420
DOI:10.1016/j.cmet.2011.02.011
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.cmet.2011.02.011
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1550413111000842
Get full text
Author Notes:Philipp Kulozik, Allan Jones, Frits Mattijssen, Adam J. Rose, Anja Reimann, Daniela Strzoda, Stefan Kleinsorg, Christina Raupp, Jürgen Kleinschmidt, Karin Müller-Decker, Walter Wahli, Carsten Sticht, Norbert Gretz, Christian von Loeffelholz, Martin Stockmann, Andreas Pfeiffer, Sigrid Stöhr, Geesje M. Dallinga-Thie, Peter P. Nawroth, Mauricio Berriel Diaz, and Stephan Herzig