Self-expanding nitinol renal artery stents: comparison of safety and efficacy of bare versus polyzene-F nanocoated stents in a porcine model
To investigate the safety and efficacy of a Polyzene-F nanocoat on new low-profile self-expandable nitinol stents in minipig renal arteries.
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2011
|
| In: |
CardioVascular and interventional radiology
Year: 2011, Jahrgang: 34, Pages: 139-148 |
| ISSN: | 1432-086X |
| DOI: | 10.1007/s00270-010-9987-7 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00270-010-9987-7
|
| Verfasserangaben: | P. Kurz, U. Stampfl, P. Christoph, C. Henn, S. Satzl, B. Radeleff, I. Berger, G.M. Richter |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1809718511 | ||
| 003 | DE-627 | ||
| 005 | 20220820221729.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 220711s2011 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00270-010-9987-7 |2 doi | |
| 035 | |a (DE-627)1809718511 | ||
| 035 | |a (DE-599)KXP1809718511 | ||
| 035 | |a (OCoLC)1341463829 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Kurz, Patrick |d 1976- |e VerfasserIn |0 (DE-588)1052729584 |0 (DE-627)789027135 |0 (DE-576)408511524 |4 aut | |
| 245 | 1 | 0 | |a Self-expanding nitinol renal artery stents |b comparison of safety and efficacy of bare versus polyzene-F nanocoated stents in a porcine model |c P. Kurz, U. Stampfl, P. Christoph, C. Henn, S. Satzl, B. Radeleff, I. Berger, G.M. Richter |
| 264 | 1 | |c 2011 | |
| 300 | |a 10 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Published online: 26 October 2010 | ||
| 500 | |a Gesehen am 11.07.2022 | ||
| 520 | |a To investigate the safety and efficacy of a Polyzene-F nanocoat on new low-profile self-expandable nitinol stents in minipig renal arteries. | ||
| 520 | |a Objective: To investigate the safety and efficacy of a Polyzene-F nanocoat on new low-profile self-expandable nitinol stents in minipig renal arteries. Materials and Methods: Ten bare nitinol stents (BNS) and 10 stents coated with a 50 nm-thin Polyzene-F coating were randomly implanted into renal arteries of 10 minipigs (4- and 12-week follow-up, 5 animals/group). Thrombogenicity, on-stent surface endothelialization, vessel wall injury, late in-stent stenosis, and peristrut vessel wall inflammation were determined by quantitative angiography and postmortem histomorphometry. Results: In 6 of 10 BNS, >50% stenosis was found, but no stenosis was found in stents with a nanothin Polyzene-F coating. Histomorphometry showed a statistically significant (p < 0.05) different average maximum luminal loss of 55.16% ± 8.43% at 12 weeks in BNS versus 39.77% ± 7.41% in stents with a nanothin Polyzene-F coating. Stents with a nanothin Polyzene-F coating had a significantly (p < 0.05) lower inflammation score after 12 weeks, 1.31 ± 1.17 versus 2.17 ± 0.85 in BNS. The results for vessel wall injury (0.6 ± 0.58 for Polyzene-F-coated stents; 0.72 ± 0.98 for BNS) and re-endothelialization, (1.16 ± 0.43 and 1.23 ± 0.54, respectively) were not statistically significant at 12-week follow-up. No thrombus deposition was observed on the stents at either follow-up time point. Conclusion: Nitinol stents with a nanothin Polyzene-F coating successfully decreased in-stent stenosis and vessel wall inflammation compared with BNS. Endothelialization and vessel wall injury were found to be equal. These studies warrant long-term pig studies (≥120 days) because 12 weeks may not be sufficient time for complete healing; thereafter, human studies may be warranted. | ||
| 650 | 4 | |a In-stent stenosis | |
| 650 | 4 | |a Interventional radiology | |
| 650 | 4 | |a Intimal hyperplasia | |
| 650 | 4 | |a Nitinol | |
| 650 | 4 | |a Polyzene-F | |
| 650 | 4 | |a Renal artery stents | |
| 700 | 1 | |a Stampfl, Ulrike |d 1978- |e VerfasserIn |0 (DE-588)132557711 |0 (DE-627)523645104 |0 (DE-576)261999664 |4 aut | |
| 700 | 1 | |a Christoph, Patricia |d 1977- |e VerfasserIn |0 (DE-588)139612351 |0 (DE-627)703397877 |0 (DE-576)312452446 |4 aut | |
| 700 | 1 | |a Henn, C. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Satzl, Stefanie |d 1978- |e VerfasserIn |0 (DE-588)133960951 |0 (DE-627)558836461 |0 (DE-576)276903714 |4 aut | |
| 700 | 1 | |a Radeleff, Boris |d 1969- |e VerfasserIn |0 (DE-588)123910846 |0 (DE-627)706470826 |0 (DE-576)293938504 |4 aut | |
| 700 | 1 | |a Berger, Irina |e VerfasserIn |0 (DE-588)1230828818 |0 (DE-627)1753176654 |4 aut | |
| 700 | 1 | |a Richter, Götz Martin |e VerfasserIn |0 (DE-588)1068606568 |0 (DE-627)820513555 |0 (DE-576)427924057 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t CardioVascular and interventional radiology |d Berlin : Springer, 1978 |g 34(2011), Seite 139-148 |h Online-Ressource |w (DE-627)253390451 |w (DE-600)1458490-6 |w (DE-576)072283483 |x 1432-086X |7 nnas |a Self-expanding nitinol renal artery stents comparison of safety and efficacy of bare versus polyzene-F nanocoated stents in a porcine model |
| 773 | 1 | 8 | |g volume:34 |g year:2011 |g pages:139-148 |g extent:10 |a Self-expanding nitinol renal artery stents comparison of safety and efficacy of bare versus polyzene-F nanocoated stents in a porcine model |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00270-010-9987-7 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20220711 | ||
| 993 | |a Article | ||
| 994 | |a 2011 | ||
| 998 | |g 1068606568 |a Richter, Götz Martin |m 1068606568:Richter, Götz Martin |d 50000 |e 50000PR1068606568 |k 0/50000/ |p 8 |y j | ||
| 998 | |g 1230828818 |a Berger, Irina |m 1230828818:Berger, Irina |d 50000 |e 50000PB1230828818 |k 0/50000/ |p 7 | ||
| 998 | |g 123910846 |a Radeleff, Boris |m 123910846:Radeleff, Boris |d 910000 |d 911400 |e 910000PR123910846 |e 911400PR123910846 |k 0/910000/ |k 1/910000/911400/ |p 6 | ||
| 998 | |g 132557711 |a Stampfl, Ulrike |m 132557711:Stampfl, Ulrike |d 910000 |d 911400 |e 910000PS132557711 |e 911400PS132557711 |k 0/910000/ |k 1/910000/911400/ |p 2 | ||
| 999 | |a KXP-PPN1809718511 |e 4163946373 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"type":{"bibl":"article-journal","media":"Online-Ressource"},"note":["Published online: 26 October 2010","Gesehen am 11.07.2022"],"title":[{"subtitle":"comparison of safety and efficacy of bare versus polyzene-F nanocoated stents in a porcine model","title":"Self-expanding nitinol renal artery stents","title_sort":"Self-expanding nitinol renal artery stents"}],"person":[{"role":"aut","given":"Patrick","roleDisplay":"VerfasserIn","family":"Kurz","display":"Kurz, Patrick"},{"display":"Stampfl, Ulrike","family":"Stampfl","roleDisplay":"VerfasserIn","given":"Ulrike","role":"aut"},{"role":"aut","given":"Patricia","family":"Christoph","display":"Christoph, Patricia","roleDisplay":"VerfasserIn"},{"roleDisplay":"VerfasserIn","display":"Henn, C.","family":"Henn","given":"C.","role":"aut"},{"role":"aut","given":"Stefanie","display":"Satzl, Stefanie","family":"Satzl","roleDisplay":"VerfasserIn"},{"role":"aut","given":"Boris","roleDisplay":"VerfasserIn","family":"Radeleff","display":"Radeleff, Boris"},{"display":"Berger, Irina","family":"Berger","roleDisplay":"VerfasserIn","role":"aut","given":"Irina"},{"given":"Götz Martin","role":"aut","family":"Richter","display":"Richter, Götz Martin","roleDisplay":"VerfasserIn"}],"recId":"1809718511","language":["eng"],"id":{"eki":["1809718511"],"doi":["10.1007/s00270-010-9987-7"]},"physDesc":[{"extent":"10 S."}],"name":{"displayForm":["P. Kurz, U. Stampfl, P. Christoph, C. Henn, S. Satzl, B. Radeleff, I. Berger, G.M. Richter"]},"relHost":[{"type":{"bibl":"periodical","media":"Online-Ressource"},"title":[{"title_sort":"CardioVascular and interventional radiology","subtitle":"CVIR","title":"CardioVascular and interventional radiology"}],"note":["Gesehen am 27. November 2017","Fortsetzung der Druck-Ausgabe","Ungezählte Beil. ab 20.1997: Supplement"],"titleAlt":[{"title":"CVIR"},{"title":"Cardiovascular radiology"},{"title":"CardioVascular & interventional radiology"}],"recId":"253390451","physDesc":[{"extent":"Online-Ressource"}],"language":["eng"],"id":{"eki":["253390451"],"zdb":["1458490-6"],"issn":["1432-086X"]},"part":{"year":"2011","volume":"34","extent":"10","text":"34(2011), Seite 139-148","pages":"139-148"},"disp":"Self-expanding nitinol renal artery stents comparison of safety and efficacy of bare versus polyzene-F nanocoated stents in a porcine modelCardioVascular and interventional radiology","pubHistory":["1.1978 -"],"origin":[{"dateIssuedDisp":"1978-","publisher":"Springer ; Springer","dateIssuedKey":"1978","publisherPlace":"Berlin ; Heidelberg ; New York, NY"}]}],"origin":[{"dateIssuedKey":"2011","dateIssuedDisp":"2011"}]} | ||
| SRT | |a KURZPATRICSELFEXPAND2011 | ||