Glycated and carbamylated albumin are more "nephrotoxic" than unmodified albumin in the amphibian kidney

There is increasing evidence that proteins in tubular fluid are “nephrotoxic.” In vivo it is difficult to study protein loading of tubular epithelial cells in isolation, i.e., without concomitant glomerular damage or changes of renal hemodynamics, etc. Recently, a unique amphibian model has been des...

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Main Authors: Groß-Weissmann, Marie-Luise (Author) , Piecha, Grzegorz (Author) , Bierhaus, Angelika (Author) , Hanke, W. (Author) , Henle, T. (Author) , Schirmacher, Peter (Author) , Ritz, Eberhard (Author)
Format: Article (Journal)
Language:English
Published: March 2, 2011
In: American journal of physiology. Renal physiology
Year: 2011, Volume: 301, Issue: 3, Pages: F476-F485
ISSN:1522-1466
DOI:10.1152/ajprenal.00342.2010
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1152/ajprenal.00342.2010
Verlag, lizenzpflichtig, Volltext: https://journals.physiology.org/doi/full/10.1152/ajprenal.00342.2010
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Author Notes:M.-L. Gross, G. Piecha, A. Bierhaus, W. Hanke, T. Henle, P. Schirmacher, and E. Ritz