Glycated and carbamylated albumin are more "nephrotoxic" than unmodified albumin in the amphibian kidney
There is increasing evidence that proteins in tubular fluid are “nephrotoxic.” In vivo it is difficult to study protein loading of tubular epithelial cells in isolation, i.e., without concomitant glomerular damage or changes of renal hemodynamics, etc. Recently, a unique amphibian model has been des...
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| Main Authors: | , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
March 2, 2011
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| In: |
American journal of physiology. Renal physiology
Year: 2011, Volume: 301, Issue: 3, Pages: F476-F485 |
| ISSN: | 1522-1466 |
| DOI: | 10.1152/ajprenal.00342.2010 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1152/ajprenal.00342.2010 Verlag, lizenzpflichtig, Volltext: https://journals.physiology.org/doi/full/10.1152/ajprenal.00342.2010 |
| Author Notes: | M.-L. Gross, G. Piecha, A. Bierhaus, W. Hanke, T. Henle, P. Schirmacher, and E. Ritz |