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Updating the approaches to define susceptibility and resistance to anti-tuberculosis agents: implications for diagnosis and treatment

Tweetable abstract ERSpublications - click to tweetInappropriately high breakpoints have resulted in systematic false-susceptible AST results to anti-TB drugs. MIC, PK/PD and clinical outcome data should be combined when setting breakpoints to minimise the emergence and spread of antimicrobial resis...

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Main Authors: Georghiou, Sophia B. (Author) , Rodwell, Timothy C. (Author) , Korobitsyn, Alexei (Author) , Abbadi, Said H. (Author) , Ajbani, Kanchan (Author) , Alffenaar, Jan-Willem (Author) , Alland, David (Author) , Alvarez, Nataly (Author) , Andres, Sönke (Author) , Ardizzoni, Elisa (Author) , Aubry, Alexandra (Author) , Baldan, Rossella (Author) , Ballif, Marie (Author) , Barilar, Ivan (Author) , Böttger, Erik C. (Author) , Chakravorty, Soumitesh (Author) , Claxton, Pauline M. (Author) , Cirillo, Daniela M. (Author) , Comas, Iñaki (Author) , Coulter, Chris (Author) , Denkinger, Claudia M. (Author) , Derendinger, Brigitta (Author) , Desmond, Edward P. (Author) , Steenwinkel, Jurriaan E. M. de (Author) , Dheda, Keertan (Author) , Diacon, Andreas H. (Author) , Dolinger, David L. (Author) , Dooley, Kelly E. (Author) , Egger, Matthias (Author) , Ehsani, Soudeh (Author) , Farhat, Maha R. (Author) , Fattorini, Lanfranco (Author) , Finci, Iris (Author) , Ray, Laure Fournier Le (Author) , Furió, Victoria (Author) , Groenheit, Ramona (Author) , Gumbo, Tawanda (Author) , Heysell, Scott K. (Author) , Hillemann, Doris (Author) , Hoffmann, Harald (Author) , Hsueh, Po-Ren (Author) , Hu, Yi (Author) , Huang, Hairong (Author) , Hussain, Alamdar (Author) , Ismail, Farzana (Author) , Izumi, Kiyohiko (Author) , Jagielski, Tomasz (Author) , Johnson, John L. (Author) , Kambli, Priti (Author) , Kaniga, Koné (Author) , Karunaratne, G. H. R. Eranga (Author) , Sharma, Meenu Kaushal (Author) , Keller, Peter M. (Author) , Kelly, Ellis C. (Author) , Kholina, Margarita (Author) , Kohli, Mikashmi (Author) , Kranzer, Katharina (Author) , Laurenson, Ian F. (Author) , Limberis, Jason (Author) , Lin, S.-Y. Grace (Author) , Liu, Yongge (Author) , López-Gavín, Alexandre (Author) , Lyander, Anna (Author) , Machado, Diana (Author) , Martinez, Elena (Author) , Masood, Faisal (Author) , Mitarai, Satoshi (Author) , Mvelase, Nomonde R. (Author) , Niemann, Stefan (Author) , Nikolayevskyy, Vladyslav (Author) , Maurer, Florian Peter (Author) , Merker, Matthias (Author) , Miotto, Paolo (Author) , Omar, Shaheed V. (Author) , Otto-Knapp, Ralf (Author) , Palaci, Moisés (Author) , Gutiérrez, Juan José Palacios (Author) , Peacock, Sharon J. (Author) , Peloquin, Charles A. (Author) , Perera, Jennifer (Author) , Pierre-Audigier, Catherine (Author) , Pholwat, Suporn (Author) , Posey, James E. (Author) , Prammananan, Therdsak (Author) , Rigouts, Leen (Author) , Robledo, Jaime (Author) , Rockwood, Neesha (Author) , Rodrigues, Camilla (Author) , Salfinger, Max (Author) , Schechter, Marcos C. (Author) , Seifert, Marva (Author) , Sengstake, Sarah (Author) , Shinnick, Thomas (Author) , Shubladze, Natalia (Author) , Sintchenko, Vitali (Author) , Sirgel, Frederick (Author) , Somasundaram, Sulochana (Author) , Sterling, Timothy R. (Author) , Spitaleri, Andrea (Author) , Streicher, Elizabeth (Author) , Supply, Philip (Author) , Svensson, Erik (Author) , Tagliani, Elisa (Author) , Tahseen, Sabira (Author) , Takaki, Akiko (Author) , Theron, Grant (Author) , Torrea, Gabriela (Author) , Deun, Armand Van (Author) , Ingen, Jakko van (Author) , Rie, Annelies Van (Author) , Soolingen, Dick van (Author) , Jr, Roger Vargas (Author) , Venter, Amour (Author) , Veziris, Nicolas (Author) , Villellas, Cristina (Author) , Viveiros, Miguel (Author) , Warren, Robin (Author) , Wen, Shu'an (Author) , Werngren, Jim (Author) , Wilkinson, Robert J. (Author) , Yang, Caie (Author) , Yılmaz, F. Ferda (Author) , Zhang, Tingting (Author) , Zimenkov, Danila (Author) , Ismail, Nazir (Author) , Köser, Claudio U. (Author) , Schön, Thomas (Author)
Format: Article (Journal)
Language:English
Published: April 14, 2022
In: The European respiratory journal
Year: 2022, Volume: 59, Issue: 4, Pages: 1-11
ISSN:1399-3003
DOI:10.1183/13993003.00166-2022
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1183/13993003.00166-2022
Verlag, lizenzpflichtig, Volltext: https://erj.ersjournals.com/content/59/4/2200166
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Author Notes:Antimycobacterial Susceptibility Testing Group*

MARC

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SRT |a GEORGHIOUSUPDATINGTH1420 

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