The interleukin-7 receptor α chain contributes to altered homeostasis of regulatory T cells in multiple sclerosis
Treg homeostasis is disturbed in multiple sclerosis (MS). Frequencies of recent thymic emigrant (RTE)-Treg are reduced and the disparity between RTE-Treg and long-lived memory Treg coincides with the MS-associated Treg defect, as shown previously.
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| Main Authors: | , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2011
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| In: |
European journal of immunology
Year: 2011, Volume: 41, Issue: 3, Pages: 845-853 |
| ISSN: | 1521-4141 |
| DOI: | 10.1002/eji.201041139 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/eji.201041139 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/10.1002/eji.201041139 |
| Author Notes: | Jürgen Haas, Mirjam Korporal, Alexander Schwarz, Bettina Balint and Brigitte Wildemann |
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| 520 | |a Treg homeostasis is disturbed in multiple sclerosis (MS). Frequencies of recent thymic emigrant (RTE)-Treg are reduced and the disparity between RTE-Treg and long-lived memory Treg coincides with the MS-associated Treg defect, as shown previously. | ||
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