Natural killer cells are scarce in colorectal carcinoma tissue despite high levels of chemokines and cytokines

Purpose: Tumor infiltrating T lymphocytes in colorectal cancer (CRC) have prognostic impact, but the role of natural killer (NK) cells in CRC tissue is unclear. The contribution of intratumoral cytokines and chemokines in shaping the composition of the inflammatory lymphocytic infiltrate is also unc...

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Main Authors: Halama, Niels (Author) , Braun, Monika (Author) , Kahlert, Christoph (Author) , Spille, Anna (Author) , Quack, Christian (Author) , Rahbari, Nuh Nabi (Author) , Koch, Moritz (Author) , Weitz, Jürgen (Author) , Kloor, Matthias (Author) , Zörnig, Inka (Author) , Schirmacher, Peter (Author) , Brand, Karsten (Author) , Grabe, Niels (Author) , Falk, Christine S. (Author)
Format: Article (Journal)
Language:English
Published: February 15, 2011
In: Clinical cancer research
Year: 2011, Volume: 17, Issue: 4, Pages: 678-689
ISSN:1557-3265
DOI:10.1158/1078-0432.CCR-10-2173
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1158/1078-0432.CCR-10-2173
Verlag, lizenzpflichtig, Volltext: https://aacrjournals.org/clincancerres/article/17/4/678/11942/Natural-Killer-Cells-are-Scarce-in-Colorectal
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Author Notes:Niels Halama, Monika Braun, Christoph Kahlert, Anna Spille, Christian Quack, Nuh Rahbari, Moritz Koch, Jürgen Weitz, Matthias Kloor, Inka Zoernig, Peter Schirmacher, Karsten Brand, Niels Grabe, and Christine S. Falk