Organization of SNAREs within the Golgi Stack
Antero- and retrograde cargo transport through the Golgi requires a series of membrane fusion events. Fusion occurs at the cis- and trans-side and along the rims of the Golgi stack. Four functional SNARE complexes have been identified mediating lipid bilayer merger in the Golgi. Their function is ti...
Gespeichert in:
| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
July 18, 2011
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| In: |
Cold Spring Harbor perspectives in biology
Year: 2011, Jahrgang: 3, Heft: 10, Pages: 1-18 |
| ISSN: | 1943-0264 |
| DOI: | 10.1101/cshperspect.a005249 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1101/cshperspect.a005249 Verlag, lizenzpflichtig, Volltext: http://cshperspectives.cshlp.org/content/3/10/a005249 
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| Verfasserangaben: | Jörg Malsam and Thomas H. Söllner |
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| 520 | |a Antero- and retrograde cargo transport through the Golgi requires a series of membrane fusion events. Fusion occurs at the cis- and trans-side and along the rims of the Golgi stack. Four functional SNARE complexes have been identified mediating lipid bilayer merger in the Golgi. Their function is tightly controlled by a series of reactions involving vesicle tethering and SM proteins. This network of protein interactions spatially and temporally determines the specificity of transport vesicle targeting and fusion within the Golgi. | ||
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