Everolimus in heart transplantation: an update
The evidence base relating to the use of everolimus in heart transplantation has expanded considerably in recent years, providing clinically relevant information regarding its use in clinical practice. Unless there are special considerations to take into account, all de novo heart transplant patient...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
05 Dec 2013
|
| In: |
Journal of transplantation
Year: 2013, Pages: 1-13 |
| ISSN: | 2090-0015 |
| DOI: | 10.1155/2013/683964 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1155/2013/683964 Verlag, lizenzpflichtig, Volltext: https://www.hindawi.com/journals/jtrans/2013/683964/ 
|
| Verfasserangaben: | Stephan W. Hirt, Christoph Bara, Markus J. Barten, Tobias Deuse, Andreas O. Doesch, Ingo Kaczmarek, Uwe Schulz, Jörg Stypmann, Assad Haneya, and Hans B. Lehmkuhl |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1814379673 | ||
| 003 | DE-627 | ||
| 005 | 20230710092347.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 220816s2013 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1155/2013/683964 |2 doi | |
| 035 | |a (DE-627)1814379673 | ||
| 035 | |a (DE-599)KXP1814379673 | ||
| 035 | |a (OCoLC)1389736950 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Hirt, Stephan W. |e VerfasserIn |0 (DE-588)1235496538 |0 (DE-627)1760506931 |4 aut | |
| 245 | 1 | 0 | |a Everolimus in heart transplantation |b an update |c Stephan W. Hirt, Christoph Bara, Markus J. Barten, Tobias Deuse, Andreas O. Doesch, Ingo Kaczmarek, Uwe Schulz, Jörg Stypmann, Assad Haneya, and Hans B. Lehmkuhl |
| 264 | 1 | |c 05 Dec 2013 | |
| 300 | |a 13 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 16.08.2022 | ||
| 520 | |a The evidence base relating to the use of everolimus in heart transplantation has expanded considerably in recent years, providing clinically relevant information regarding its use in clinical practice. Unless there are special considerations to take into account, all de novo heart transplant patients can be regarded as potential candidates for immunosuppression with everolimus and reduced-exposure calcineurin inhibitor therapy. Caution about the use of everolimus immediately after transplantation should be exercised in certain patients with the risk of severe proteinuria, with poor wound healing, or with uncontrolled severe hyperlipidemia. Initiation of everolimus in the early phase aftertransplant is not advisable in patients with severe pretransplant end-organ dysfunction or in patients on a left ventricular assist device beforetransplant who are at high risk of infection or of wound healing complications. The most frequent reason for introducing everolimus in maintenance heart transplant patients is to support minimization or withdrawal of calcineurin inhibitor therapy, for example, due to impaired renal function or malignancy. Due to its potential to inhibit the progression of cardiac allograft vasculopathy and to reduce cytomegalovirus infection, everolimus should be initiated as soon as possible after heart transplantation. Immediate and adequate reduction of CNI exposure is mandatory from the start of everolimus therapy. | ||
| 700 | 1 | |a Bara, Christoph |e VerfasserIn |4 aut | |
| 700 | 1 | |a Barten, Markus J. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Deuse, Tobias |e VerfasserIn |4 aut | |
| 700 | 1 | |a Dösch, Andreas |d 1976- |e VerfasserIn |0 (DE-588)129172758 |0 (DE-627)390355798 |0 (DE-576)297522310 |4 aut | |
| 700 | 1 | |a Kaczmarek, Ingo |e VerfasserIn |4 aut | |
| 700 | 1 | |a Schulz, Uwe |e VerfasserIn |4 aut | |
| 700 | 1 | |a Stypmann, Jörg |e VerfasserIn |4 aut | |
| 700 | 1 | |a Haneya, Assad |e VerfasserIn |4 aut | |
| 700 | 1 | |a Lehmkuhl, Hans B. |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of transplantation |d [Hoboken, NJ : Wiley], 2009 |g (2013), Artikel-ID e683964, Seite 1-13 |h Online-Ressource |w (DE-627)604082061 |w (DE-600)2503421-2 |w (DE-576)308347536 |x 2090-0015 |7 nnas |a Everolimus in heart transplantation an update |
| 773 | 1 | 8 | |g year:2013 |g elocationid:e683964 |g pages:1-13 |g extent:13 |a Everolimus in heart transplantation an update |
| 856 | 4 | 0 | |u https://doi.org/10.1155/2013/683964 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.hindawi.com/journals/jtrans/2013/683964/ |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20220816 | ||
| 993 | |a Article | ||
| 998 | |g 129172758 |a Dösch, Andreas |m 129172758:Dösch, Andreas |d 910000 |d 910100 |d 50000 |e 910000PD129172758 |e 910100PD129172758 |e 50000PD129172758 |k 0/910000/ |k 1/910000/910100/ |k 0/50000/ |p 5 | ||
| 999 | |a KXP-PPN1814379673 |e 4179537990 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"person":[{"role":"aut","roleDisplay":"VerfasserIn","display":"Hirt, Stephan W.","given":"Stephan W.","family":"Hirt"},{"given":"Christoph","family":"Bara","role":"aut","display":"Bara, Christoph","roleDisplay":"VerfasserIn"},{"family":"Barten","given":"Markus J.","display":"Barten, Markus J.","roleDisplay":"VerfasserIn","role":"aut"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Deuse, Tobias","given":"Tobias","family":"Deuse"},{"given":"Andreas","family":"Dösch","role":"aut","roleDisplay":"VerfasserIn","display":"Dösch, Andreas"},{"given":"Ingo","family":"Kaczmarek","role":"aut","display":"Kaczmarek, Ingo","roleDisplay":"VerfasserIn"},{"given":"Uwe","family":"Schulz","role":"aut","display":"Schulz, Uwe","roleDisplay":"VerfasserIn"},{"roleDisplay":"VerfasserIn","display":"Stypmann, Jörg","role":"aut","family":"Stypmann","given":"Jörg"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Haneya, Assad","given":"Assad","family":"Haneya"},{"family":"Lehmkuhl","given":"Hans B.","roleDisplay":"VerfasserIn","display":"Lehmkuhl, Hans B.","role":"aut"}],"title":[{"subtitle":"an update","title":"Everolimus in heart transplantation","title_sort":"Everolimus in heart transplantation"}],"recId":"1814379673","language":["eng"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"note":["Gesehen am 16.08.2022"],"name":{"displayForm":["Stephan W. Hirt, Christoph Bara, Markus J. Barten, Tobias Deuse, Andreas O. Doesch, Ingo Kaczmarek, Uwe Schulz, Jörg Stypmann, Assad Haneya, and Hans B. Lehmkuhl"]},"id":{"doi":["10.1155/2013/683964"],"eki":["1814379673"]},"origin":[{"dateIssuedKey":"2013","dateIssuedDisp":"05 Dec 2013"}],"relHost":[{"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"publisher":"Wiley] ; Hindawi","dateIssuedKey":"2024","dateIssuedDisp":"2024-","publisherPlace":"[Hoboken, NJ ; New York, NY"}],"id":{"eki":["604082061"],"doi":["10.1155/JTRAN"],"zdb":["2503421-2"],"issn":["2090-0015"]},"pubHistory":["2009-"],"part":{"year":"2013","pages":"1-13","text":"(2013), Artikel-ID e683964, Seite 1-13","extent":"13"},"type":{"bibl":"periodical","media":"Online-Ressource"},"note":["Gesehen am 21.09.10"],"disp":"Everolimus in heart transplantation an updateJournal of transplantation","recId":"604082061","language":["eng"],"title":[{"title_sort":"Journal of transplantation","title":"Journal of transplantation"}]}],"physDesc":[{"extent":"13 S."}]} | ||
| SRT | |a HIRTSTEPHAEVEROLIMUS0520 | ||