Adipocyte-specific inactivation of Acyl-CoA synthetase fatty acid transport protein 4 (Fatp4) in mice causes adipose hypertrophy and alterations in metabolism of complex lipids under high fat diet
Fatp4 exhibits acyl-CoA synthetase activity and is thereby able to catalyze the activation of fatty acids for further metabolism. However, its actual function in most tissues remains unresolved, and its role in cellular fatty acid uptake is still controversial. To characterize Fatp4 functions in adi...
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| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
July 31, 2011
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| In: |
The journal of biological chemistry
Year: 2011, Volume: 286, Issue: 41, Pages: 35578-35587 |
| ISSN: | 1083-351X |
| DOI: | 10.1074/jbc.M111.226530 |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.1074/jbc.M111.226530 Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S0021925820737646 |
| Author Notes: | Lena-Solveig Lenz, Jana Marx, Walee Chamulitrat, Iris Kaiser, Hermann-Josef Gröne, Gerhard Liebisch, Gerd Schmitz, Christoph Elsing, Beate K. Straub, Joachim Füllekrug, Wolfgang Stremmel, and Thomas Herrmann |