Classification of skin sensitizing substances: a comparison between approaches used by the DFG-MAK Commission and the European Union legislation
A systematic classification of substances (or mixtures of substances) with regard to various toxicological endpoints is a prerequisite for the implementation of occupational safety strategies. As its principal task the “Commission for the Investigation of Health Hazards of Chemical Compounds in the...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2011
|
| In: |
Regulatory toxicology and pharmacology
Year: 2011, Jahrgang: 61, Heft: 1, Pages: 1-8 |
| ISSN: | 1096-0295 |
| DOI: | 10.1016/j.yrtph.2011.06.008 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.yrtph.2011.06.008 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0273230011001474 
|
| Verfasserangaben: | H. Lessmann, W. Uter, T. L. Diepgen, H. Drexler, M. Fartasch, H. Greim, A. Hartwig, P. Kreis, E. Löser, R. Merget, H. Merk, D. Nowak, A. Rothe, G. Stropp, A. Schnuch |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1814566376 | ||
| 003 | DE-627 | ||
| 005 | 20230710121851.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 220817s2011 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.yrtph.2011.06.008 |2 doi | |
| 035 | |a (DE-627)1814566376 | ||
| 035 | |a (DE-599)KXP1814566376 | ||
| 035 | |a (OCoLC)1389793079 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Lessmann, Holger |e VerfasserIn |0 (DE-588)1265613370 |0 (DE-627)1814566171 |4 aut | |
| 245 | 1 | 0 | |a Classification of skin sensitizing substances |b a comparison between approaches used by the DFG-MAK Commission and the European Union legislation |c H. Lessmann, W. Uter, T. L. Diepgen, H. Drexler, M. Fartasch, H. Greim, A. Hartwig, P. Kreis, E. Löser, R. Merget, H. Merk, D. Nowak, A. Rothe, G. Stropp, A. Schnuch |
| 264 | 1 | |c 2011 | |
| 300 | |a 8 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 17.08.2022 | ||
| 520 | |a A systematic classification of substances (or mixtures of substances) with regard to various toxicological endpoints is a prerequisite for the implementation of occupational safety strategies. As its principal task the “Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area” of the “Deutsche Forschungsgemeinschaft” (DFG-MAK Commission) derives and recommends maximum workplace concentrations and biological tolerance values (MAK and BAT values) based exclusively on scientific arguments. Several endpoints are evaluated separately in detail, e.g. carcinogenicity, risks during pregnancy, germ cell mutagenicity or contribution to systemic toxicity after cutaneous absorption. Skin- and airway sensitization is also considered; the present paper focuses on these two endpoints. | ||
| 650 | 4 | |a Classification | |
| 650 | 4 | |a DFG-MAK Commission | |
| 650 | 4 | |a EU legislation | |
| 650 | 4 | |a Skin sensitization | |
| 700 | 1 | |a Uter, W. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Diepgen, Thomas L. |d 1953-2020 |e VerfasserIn |0 (DE-588)120024136 |0 (DE-627)080392725 |0 (DE-576)166354066 |4 aut | |
| 700 | 1 | |a Drexler, H. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Fartasch, M. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Greim, H. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Hartwig, A. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Kreis, P. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Löser, E. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Merget, R. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Merk, H. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Nowak, D. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Rothe, A. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Stropp, G. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Schnuch, A. |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Regulatory toxicology and pharmacology |d Amsterdam [u.a.] : Elsevier, 1981 |g 61(2011), 1, Seite 1-8 |h Online-Ressource |w (DE-627)26812812X |w (DE-600)1471700-1 |w (DE-576)264423518 |x 1096-0295 |7 nnas |a Classification of skin sensitizing substances a comparison between approaches used by the DFG-MAK Commission and the European Union legislation |
| 773 | 1 | 8 | |g volume:61 |g year:2011 |g number:1 |g pages:1-8 |g extent:8 |a Classification of skin sensitizing substances a comparison between approaches used by the DFG-MAK Commission and the European Union legislation |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.yrtph.2011.06.008 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.sciencedirect.com/science/article/pii/S0273230011001474 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20220817 | ||
| 993 | |a Article | ||
| 994 | |a 2011 | ||
| 998 | |g 120024136 |a Diepgen, Thomas L. |m 120024136:Diepgen, Thomas L. |d 910000 |d 911900 |e 910000PD120024136 |e 911900PD120024136 |k 0/910000/ |k 1/910000/911900/ |p 3 | ||
| 999 | |a KXP-PPN1814566376 |e 4180118238 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"id":{"eki":["1814566376"],"doi":["10.1016/j.yrtph.2011.06.008"]},"origin":[{"dateIssuedDisp":"2011","dateIssuedKey":"2011"}],"name":{"displayForm":["H. Lessmann, W. Uter, T. L. Diepgen, H. Drexler, M. Fartasch, H. Greim, A. Hartwig, P. Kreis, E. Löser, R. Merget, H. Merk, D. Nowak, A. Rothe, G. Stropp, A. Schnuch"]},"relHost":[{"pubHistory":["1.1981 -"],"part":{"text":"61(2011), 1, Seite 1-8","volume":"61","extent":"8","year":"2011","issue":"1","pages":"1-8"},"note":["Gesehen am 20.02.20"],"type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"Classification of skin sensitizing substances a comparison between approaches used by the DFG-MAK Commission and the European Union legislationRegulatory toxicology and pharmacology","language":["eng"],"corporate":[{"display":"International Society of Regulatory Toxicology and Pharmacology","roleDisplay":"Herausgebendes Organ","role":"isb"}],"recId":"26812812X","title":[{"title_sort":"Regulatory toxicology and pharmacology","title":"Regulatory toxicology and pharmacology","subtitle":"official journal of the International Society for Regulatory Toxicology and Pharmacology"}],"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"publisherPlace":"Amsterdam [u.a.] ; Orlando, Fla.","publisher":"Elsevier ; Academic Press","dateIssuedKey":"1981","dateIssuedDisp":"1981-"}],"id":{"issn":["1096-0295"],"zdb":["1471700-1"],"eki":["26812812X"]}}],"physDesc":[{"extent":"8 S."}],"title":[{"title_sort":"Classification of skin sensitizing substances","subtitle":"a comparison between approaches used by the DFG-MAK Commission and the European Union legislation","title":"Classification of skin sensitizing substances"}],"person":[{"family":"Lessmann","given":"Holger","display":"Lessmann, Holger","roleDisplay":"VerfasserIn","role":"aut"},{"display":"Uter, W.","roleDisplay":"VerfasserIn","role":"aut","family":"Uter","given":"W."},{"given":"Thomas L.","family":"Diepgen","role":"aut","roleDisplay":"VerfasserIn","display":"Diepgen, Thomas L."},{"role":"aut","display":"Drexler, H.","roleDisplay":"VerfasserIn","given":"H.","family":"Drexler"},{"display":"Fartasch, M.","roleDisplay":"VerfasserIn","role":"aut","family":"Fartasch","given":"M."},{"family":"Greim","given":"H.","roleDisplay":"VerfasserIn","display":"Greim, H.","role":"aut"},{"family":"Hartwig","given":"A.","display":"Hartwig, A.","roleDisplay":"VerfasserIn","role":"aut"},{"display":"Kreis, P.","roleDisplay":"VerfasserIn","role":"aut","family":"Kreis","given":"P."},{"role":"aut","display":"Löser, E.","roleDisplay":"VerfasserIn","given":"E.","family":"Löser"},{"display":"Merget, R.","roleDisplay":"VerfasserIn","role":"aut","family":"Merget","given":"R."},{"role":"aut","roleDisplay":"VerfasserIn","display":"Merk, H.","given":"H.","family":"Merk"},{"display":"Nowak, D.","roleDisplay":"VerfasserIn","role":"aut","family":"Nowak","given":"D."},{"family":"Rothe","given":"A.","display":"Rothe, A.","roleDisplay":"VerfasserIn","role":"aut"},{"roleDisplay":"VerfasserIn","display":"Stropp, G.","role":"aut","family":"Stropp","given":"G."},{"roleDisplay":"VerfasserIn","display":"Schnuch, A.","role":"aut","family":"Schnuch","given":"A."}],"language":["eng"],"recId":"1814566376","type":{"media":"Online-Ressource","bibl":"article-journal"},"note":["Gesehen am 17.08.2022"]} | ||
| SRT | |a LESSMANNHOCLASSIFICA2011 | ||