An RNAi screen identifies USP2 as a factor required for TNF-α-induced NF-κB signaling

Tumor necrosis factor α (TNF-α) signaling pathways play important roles during tumorigenesis and inflammation. Ubiquitin-dependent processes are central to the regulation of TNF-α and nuclear factor κB (NF-κB) signaling. We performed a targeted siRNA screen for ubiquitin-specific proteases (USPs) an...

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Bibliographic Details

Main Authors:	Oliver Metzig, Marie (Author) , Nickles, Dorothee (Author) , Falschlehner, Christina (Author) , Lehmann-Koch, Judith (Author) , Straub, Beate Katharina (Author) , Roth, Wilfried (Author) , Boutros, Michael (Author)
Format:	Article (Journal)
Language:	English
Published:	07 April 2011
In:	International journal of cancer Year: 2011, Volume: 129, Issue: 3, Pages: 607-618
ISSN:	1097-0215
DOI:	10.1002/ijc.26124
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/ijc.26124 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.26124
Author Notes:	Marie Metzig, Dorothee Nickles, Christina Falschlehner, Judith Lehmann-Koch, Beate K. Straub, Wilfried Roth and Michael Boutros