An RNAi screen identifies USP2 as a factor required for TNF-α-induced NF-κB signaling
Tumor necrosis factor α (TNF-α) signaling pathways play important roles during tumorigenesis and inflammation. Ubiquitin-dependent processes are central to the regulation of TNF-α and nuclear factor κB (NF-κB) signaling. We performed a targeted siRNA screen for ubiquitin-specific proteases (USPs) an...
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| Hauptverfasser: | , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
07 April 2011
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| In: |
International journal of cancer
Year: 2011, Jahrgang: 129, Heft: 3, Pages: 607-618 |
| ISSN: | 1097-0215 |
| DOI: | 10.1002/ijc.26124 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/ijc.26124 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.26124 
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| Verfasserangaben: | Marie Metzig, Dorothee Nickles, Christina Falschlehner, Judith Lehmann-Koch, Beate K. Straub, Wilfried Roth and Michael Boutros |
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