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Inositol 1,4,5-trisphosphate receptor type 1 autoantibody (ITPR1-IgG/anti-Sj)-associated autoimmune cerebellar ataxia, encephalitis and peripheral neuropathy: review of the literature

In 2014, we first described novel autoantibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1-IgG/anti-Sj) in patients with autoimmune cerebellar ataxia (ACA) in this journal. Here, we provide a review of the available literature on ITPR1-IgG/anti-Sj, covering clinical and paraclinical...

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Hauptverfasser: Jarius, Sven (VerfasserIn) , Bräuninger, Stefan (VerfasserIn) , Chung, Ha-Yeun (VerfasserIn) , Geis, Christian (VerfasserIn) , Haas, Jürgen (VerfasserIn) , Komorowski, Lars (VerfasserIn) , Wildemann, Brigitte (VerfasserIn) , Roth, Christian (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 30 July 2022
In: Journal of neuroinflammation
Year: 2022, Jahrgang: 19, Pages: 1-21
ISSN:1742-2094
DOI:10.1186/s12974-022-02545-4
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12974-022-02545-4
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Verfasserangaben:Sven Jarius, Stefan Bräuninger, Ha-Yeun Chung, Christian Geis, Jürgen Haas, Lars Komorowski, Brigitte Wildemann and Christian Roth
Beschreibung
Zusammenfassung:In 2014, we first described novel autoantibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1-IgG/anti-Sj) in patients with autoimmune cerebellar ataxia (ACA) in this journal. Here, we provide a review of the available literature on ITPR1-IgG/anti-Sj, covering clinical and paraclinical presentation, tumour association, serological findings, and immunopathogenesis.
Beschreibung:Gesehen am 19.08.2022
Beschreibung:Online Resource
ISSN:1742-2094
DOI:10.1186/s12974-022-02545-4

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