Common variants in breast cancer risk loci predispose to distinct tumor subtypes
Genome-wide association studies (GWAS) have identified multiple common breast cancer susceptibility variants. Many of these variants have differential associations by estrogen receptor (ER) status, but how these variants relate with other tumor features and intrinsic molecular subtypes is unclear.
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
04 January 2022
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| In: |
Breast cancer research
Year: 2022, Jahrgang: 24, Pages: 1-13 |
| ISSN: | 1465-542X |
| DOI: | 10.1186/s13058-021-01484-x |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13058-021-01484-x
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| Verfasserangaben: | Thomas U. Ahearn, Volker Arndt, Heiko Becher, Sabine Behrens, Hermann Brenner, Barbara Burwinkel, Jenny Chang-Claude, Audrey Jung, Rudolf Kaaks ... [und 196 weitere] |
MARC
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| 520 | |a Genome-wide association studies (GWAS) have identified multiple common breast cancer susceptibility variants. Many of these variants have differential associations by estrogen receptor (ER) status, but how these variants relate with other tumor features and intrinsic molecular subtypes is unclear. | ||
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| 650 | 4 | |a Etiologic heterogeneity | |
| 650 | 4 | |a Genetic predisposition | |
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