Long-term outcomes of mesohepatectomy for centrally located liver tumors: two-decade single-center experience
Export - BACKGROUND: Mesohepatectomy is a viable treatment option for patients diagnosed with centrally located liver tumors (CLLTs). There are several reports from Eastern centers, but few data are available on this topic from Western centers. - STUDY DESIGN: - Data of 128 consecutive patients who...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2022
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| In: |
Journal of the American College of Surgeons
Year: 2022, Jahrgang: 235, Heft: 2, Pages: 257-266 |
| ISSN: | 1879-1190 |
| DOI: | 10.1097/XCS.0000000000000209 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/XCS.0000000000000209 Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/journalacs/Fulltext/2022/08000/Long_Term_Outcomes_of_Mesohepatectomy_for.15.aspx 
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| Verfasserangaben: | Arianeb Mehrabi, MD, FACS, Ali Ramouz, MD, Mohammad Golriz, MD, MD, Elias Khajeh, MD,Thilo Hackert, MD, Beat Müller-Stich, MD, Oliver Strobel, MD, Katrin Hoffmann, MD, Markus W Büchler, MD, FACS, Liver Cancer Center Heidelberg (LCCH) |
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| 245 | 1 | 0 | |a Long-term outcomes of mesohepatectomy for centrally located liver tumors |b two-decade single-center experience |c Arianeb Mehrabi, MD, FACS, Ali Ramouz, MD, Mohammad Golriz, MD, MD, Elias Khajeh, MD,Thilo Hackert, MD, Beat Müller-Stich, MD, Oliver Strobel, MD, Katrin Hoffmann, MD, Markus W Büchler, MD, FACS, Liver Cancer Center Heidelberg (LCCH) |
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| 500 | |a Members of the Liver Cancer Center Heidelberg (LCCH): Umut Kaan Ünal, Omid Ghamarnejad, Markus Mieth, Sepehr Abbasi Dezfouli, Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany; Karl Heinz Weiss, Liver Cancer Center Heidelberg and Department of Internal Medicine, Heidelberg University Hospital, Heidelberg, Germany; De-Hua Chang, Liver Cancer Center Heidelberg and Department of Interventional Radiology, Heidelberg University Hospital, Heidelberg, Germany; Christoph Springfield, MD, Liver Cancer Center Heidelberg and National Center for Tumor Diseases, Department of Oncology, Heidelberg University Hospital, Heidelberg, Germany; Benjamin Goeppert, MD, Thomas Longerich, MD, Liver Cancer Center Heidelberg and Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany | ||
| 500 | |a Christoph Springfeld ist in der Vorlage fälschlich als Christoph Springfield angegeben | ||
| 500 | |a Gesehen am 30.08.2022 | ||
| 520 | |a Export - BACKGROUND: Mesohepatectomy is a viable treatment option for patients diagnosed with centrally located liver tumors (CLLTs). There are several reports from Eastern centers, but few data are available on this topic from Western centers. - STUDY DESIGN: - Data of 128 consecutive patients who underwent mesohepatectomy between September 2000 and September 2020 in our center were analyzed from a prospectively collected database. Patient demographic data, liver tumor characteristics, and intraoperative data were collected. In addition, posthepatectomy bile leakage (PHBL), posthepatectomy hemorrhage (PHH), posthepatectomy liver failure (PHLF), and 90-day mortality after mesohepatectomy were assessed. Long-term outcomes were also reported, and factors that may influence disease-free survival were evaluated. - RESULTS: - Of 128 patients, 113 patients (88.3%) had malignant hepatic tumors (primary and metastatic tumors in 41 [32%] and 72 [56.3%] patients, respectively), and 15 patients suffered from benign lesions (11.7%). Among the relevant surgical complications (grade B or C), PHBL was the most common complication after mesohepatectomy and occurred in 11.7% of patients, followed by PHLF in 3.1% of patients and PHH in 2.3% of patients. Only four patients (3.1%) died within 90 days after mesohepatectomy. The 5-year overall survival and overall recurrence (for malignant lesion) rates were 76.5% and 45.1%, respectively. - CONCLUSION: - Mesohepatectomy is a safe and feasible surgical treatment with low morbidity and mortality for patients with CLLT. Long-term outcomes can be improved by increased surgical expertise. | ||
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