Cover Image

Benefit of mechanical thrombectomy in acute ischemic stroke related to calcified cerebral embolus

purpose - Mechanical thrombectomies (MT) in patients with large vessel occlusion (LVO) related to calcified cerebral embolus (CCE) have been reported, through small case series, being associated with low reperfusion rate and worse outcome, compared to regular MT. The purpose of the MASC (Mechanical...

Full description

Saved in:
Bibliographic Details
Main Authors: Grand, Téodor (Author) , Dargazanli, Cyril (Author) , Papagiannaki, Chrysanthi (Author) , Bruggeman, Agnetha (Author) , Maurer, Christoph (Author) , Gascou, Gregory (Author) , Fauche, Cédric (Author) , Bourcier, Romain (Author) , Tessier, Guillaume (Author) , Blanc, Raphaël (Author) , Machaa, Malek Ben (Author) , Marnat, Gaultier (Author) , Barreau, Xavier (Author) , Ognard, Julien (Author) , Gentric, Jean-Christophe (Author) , Barbier, Charlotte (Author) , Gory, Benjamin (Author) , Rodriguez, Christine (Author) , Boulouis, Grégoire (Author) , Eugène, François (Author) , Thouant, Pierre (Author) , Ricolfi, Frederic (Author) , Janot, Kevin (Author) , Herbreteau, Denis (Author) , Eker, Omer Faruk (Author) , Cappucci, Matteo (Author) , Dobrocky, Tomas (Author) , Möhlenbruch, Markus Alfred (Author) , Demerath, Theo (Author) , Psychogios, Marios (Author) , Fischer, Sebastian (Author) , Cianfoni, Alessandro (Author) , Majoie, Charles (Author) , Emmer, Bart (Author) , Marquering, Henk (Author) , Valter, Rémi (Author) , Lenck, Stéphanie (Author) , Premat, Kévin (Author) , Cortese, Jonathan (Author) , Dormont, Didier (Author) , Sourour, Nader-Antoine (Author) , Shotar, Eimad (Author) , Samson, Yves (Author) , Clarençon, Frédéric (Author)
Format: Article (Journal)
Language:English
Published: 18 February 2022
In: Journal of neuroradiology
Year: 2022, Volume: 49, Issue: 4, Pages: 317-323
ISSN:1773-0406
DOI:10.1016/j.neurad.2022.02.006
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.neurad.2022.02.006
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0150986122000852
Get full text
Author Notes:Téodor Grand, Cyril Dargazanli, Chrysanthi Papagiannaki, Agnetha Bruggeman, Christoph Maurer, Gregory Gascou, Cédric Fauche, Romain Bourcier, Guillaume Tessier, Raphaël Blanc, Malek Ben Machaa, Gaultier Marnat, Xavier Barreau, Julien Ognard, Jean-Christophe Gentric, Charlotte Barbier, Benjamin Gory, Christine Rodriguez, Grégoire Boulouis, François Eugène, Pierre Thouant, Frederic Ricolfi, Kevin Janot, Denis Herbreteau, Omer Faruk Eker, Matteo Cappucci, Tomas Dobrocky, Markus Möhlenbruch, Theo Demerath, Marios Psychogios, Sebastian Fischer, Alessandro Cianfoni, Charles Majoie, Bart Emmer, Henk Marquering, Rémi Valter, Stéphanie Lenck, Kévin Premat, Jonathan Cortese, Didier Dormont, Nader-Antoine Sourour, Eimad Shotar, Yves Samson, Frédéric Clarençon
Description
Summary:purpose - Mechanical thrombectomies (MT) in patients with large vessel occlusion (LVO) related to calcified cerebral embolus (CCE) have been reported, through small case series, being associated with low reperfusion rate and worse outcome, compared to regular MT. The purpose of the MASC (Mechanical Thrombectomy in Acute Ischemic Stroke Related to Calcified Cerebral Embolus) study was to evaluate the incidence of CCEs treated by MT and the effectiveness of MT in this indication. - Methods - The MASC study is a retrospective multicentric (n = 37) national study gathering the cases of adult patients who underwent MT for acute ischemic stroke with LVO related to a CCE in France from January 2015 to November 2019. Reperfusion rate (mTICI ≥ 2B), complication rate and 90-day mRS were systematically collected. We then conducted a systematic review by searching for articles in PubMed, Cochrane Library, Embase and Google Scholar from January 2015 to March 2020. A meta-analysis was performed to estimate clinical outcome at 90 days, reperfusion rate and complications. - Results - We gathered data from 35 patients. Reperfusion was obtained in 57% of the cases. Good clinical outcome was observed in 28% of the patients. The meta-analysis retrieved 136 patients. Reperfusion and good clinical outcome were obtained in 50% and 29% of the cases, respectively. - Conclusion - The MASC study found worse angiographic and clinical outcomes compared to regular thrombectomies. Individual patient-based meta-analysis including the MASC findings shows a 50% reperfusion rate and a 29% of good clinical outcome.
Item Description:Gesehen am 31.08.2022
Physical Description:Online Resource
ISSN:1773-0406
DOI:10.1016/j.neurad.2022.02.006

Similar Items