Small renal cell carcinoma: oncological outcome with tumour size
OBJECTIVE: The aim of the study was to analyse oncological outcomes of patients with renal cell carcinoma (RCC) up to 4 cm in diameter. - MATERIAL AND METHODS: A consecutive series of 396 patients with small RCC was analysed. Tumours were stratified by diameter into three groups: 2 cm (n = 68) for t...
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| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
24 October 2011
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| In: |
Scandinavian journal of urology and nephrology
Year: 2011, Jahrgang: 45, Heft: 6, Pages: 432-435 |
| ISSN: | 1651-2065 |
| DOI: | 10.3109/00365599.2011.621143 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3109/00365599.2011.621143
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| Verfasserangaben: | Sascha Pahernik, Johannes Huber, Jesco Pfitzenmaier, Axel Haferkamp & Markus Hohenfellner |
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| 245 | 1 | 0 | |a Small renal cell carcinoma |b oncological outcome with tumour size |c Sascha Pahernik, Johannes Huber, Jesco Pfitzenmaier, Axel Haferkamp & Markus Hohenfellner |
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| 520 | |a OBJECTIVE: The aim of the study was to analyse oncological outcomes of patients with renal cell carcinoma (RCC) up to 4 cm in diameter. - MATERIAL AND METHODS: A consecutive series of 396 patients with small RCC was analysed. Tumours were stratified by diameter into three groups: 2 cm (n = 68) for tumours up to 2 cm, 3 cm (n = 172) for tumours between 2.1 and 3.0 cm, and 4 cm (n = 156) for tumours between 3.1 and 4.0 cm in diameter. - RESULTS: Tumour stages were distributed into pT1a in 95.6%, 91.9% and 87.0% and into pT3 in 4.4%, 8.1% and 13.0% for the 2 cm, 3 cm and 4 cm groups, respectively. Metastases at the time of diagnosis were found in 2.9% (n = 2), 7.5% (n = 13) and 9.1% (n = 14) of patients in the 2 cm, 3 cm and 4 cm groups, respectively. The tumour-specific survival was 100%, 96.9% and 94.6% at 1 year, 97.5%, 90.3% and 87.5% at 5 years and 97.5%, 87.3% and 84.1% at 10 years for the 2 cm, 3 cm and 4 cm groups, respectively (p < 0.05). - CONCLUSIONS: Negative prognostic features as well as worse oncological outcome increase with tumour diameter above 2 cm. These data have important implications when considering active surveillance of small renal tumours. | ||
| 650 | 4 | |a Adolescent | |
| 650 | 4 | |a Adult | |
| 650 | 4 | |a Aged | |
| 650 | 4 | |a Aged, 80 and over | |
| 650 | 4 | |a Carcinoma, Renal Cell | |
| 650 | 4 | |a Disease Progression | |
| 650 | 4 | |a Female | |
| 650 | 4 | |a Humans | |
| 650 | 4 | |a Kaplan-Meier Estimate | |
| 650 | 4 | |a Kidney Neoplasms | |
| 650 | 4 | |a Male | |
| 650 | 4 | |a Middle Aged | |
| 650 | 4 | |a Neoplasm Metastasis | |
| 650 | 4 | |a Neoplasm Staging | |
| 650 | 4 | |a Prognosis | |
| 650 | 4 | |a Statistics, Nonparametric | |
| 650 | 4 | |a Tumor Burden | |
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