Development and verification of an adjustment factor for determining the axial length using optical biometry in silicone oil-filled eyes

The aim of this prospective clinical study was to establish and verify an adaptation for axial length (AL) measurement in silicone oil (SO)-filled pseudophakic eyes with a Scheimpflug and partial coherence interferometry (PCI)-based biometer. The AL was measured with a Pentacam AXL (OCULUS Optikgera...

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Hauptverfasser: Auffarth, Gerd U. (VerfasserIn) , Naujokaitis, Tadas (VerfasserIn) , Blöck, Louise (VerfasserIn) , Daghbashyan, Anna (VerfasserIn) , Meis, Jan (VerfasserIn) , Augustin, Victor A. (VerfasserIn) , Khoramnia, Ramin (VerfasserIn) , Yildirim, Timur Mert (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 11 January 2022
In: Diagnostics
Year: 2022, Jahrgang: 12, Heft: 1, Pages: 1-8
ISSN:2075-4418
DOI:10.3390/diagnostics12010163
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/diagnostics12010163
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2075-4418/12/1/163
Volltext
Verfasserangaben:Gerd U. Auffarth, Tadas Naujokaitis, Louise Blöck, Anna Daghbashyan, Jan Meis, Victor A. Augustin, Ramin Khoramnia and Timur M. Yildirim

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520 |a The aim of this prospective clinical study was to establish and verify an adaptation for axial length (AL) measurement in silicone oil (SO)-filled pseudophakic eyes with a Scheimpflug and partial coherence interferometry (PCI)-based biometer. The AL was measured with a Pentacam AXL (OCULUS Optikgeräte GmbH, Wetzler, Germany) and IOLMaster 700 (Carl Zeiss Meditec, Jena, Germany). The coefficients of variation (CoV) and the mean systematic difference (95% confidence interval (CI)) between the devices were calculated. After implementing a setting for measuring AL in tamponaded eyes with a Pentacam based on data of 29 eyes, another 12 eyes were examined for verification. The mean AL obtained with the Pentacam was 25.53 ± 1.94 mm (range: 21.70 to 30.76 mm), and with IOLMaster, 24.73 ± 1.97 mm (ranged 20.84 to 29.92 mm), resulting in a mean offset of 0.80 ± 0.08 mm (95% CI: 0.77, 0.83 mm), p < 0.001. The AL values of both devices showed a strong linear correlation (r = 0.999). Verification data confirmed good agreement, with a statistically and clinically non-significant mean difference of 0.02 ± 0.04 (95% CI: −0.01, 0.05) mm, p = 0.134. We implemented a specific adaptation for obtaining reliable AL values in SO-filled eyes with the Pentacam AXL. 
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