Modular assembly of the principal microtubule nucleator γ-TuRC
The human microtubule nucleator γ-TuRC is composed of more than thirty subunits, including actin. Here the authors reveal the structural mechanism of modular γ-TuRC assembly and show a functional role of actin in microtubule nucleation.
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
25 January 2022
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| In: |
Nature Communications
Year: 2022, Jahrgang: 13, Pages: 1-16 |
| ISSN: | 2041-1723 |
| DOI: | 10.1038/s41467-022-28079-0 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s41467-022-28079-0 Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41467-022-28079-0 
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| Verfasserangaben: | Martin Würtz, Erik Zupa, Enrico S. Atorino, Annett Neuner, Anna Böhler, Ariani S. Rahadian, Bram J.A. Vermeulen, Giulia Tonon, Sebastian Eustermann, Elmar Schiebel & Stefan Pfeffer |
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| 520 | |a The human microtubule nucleator γ-TuRC is composed of more than thirty subunits, including actin. Here the authors reveal the structural mechanism of modular γ-TuRC assembly and show a functional role of actin in microtubule nucleation. | ||
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