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FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma

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Purpose - - Integrated genomics approaches have revealed at least four distinct biologic variants of medulloblastoma: WNT (wingless), SHH (sonic hedgehog), group C, and group D. Because of the remarkable clinical heterogeneity of group D tumors and the dismal prognosis of group C patients, it is vi...

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Main Authors: Remke, Marc (Author) , Hielscher, Thomas (Author) , Korshunov, Andrey (Author) , Northcott, Paul A. (Author) , Bender, Sebastian (Author) , Kool, Marcel (Author) , Westermann, Frank (Author) , Benner, Axel (Author) , Şeker-Cin, Huriye (Author) , Ryzhova, Marina (Author) , Sturm, Dominik (Author) , Witt, Hendrik (Author) , Haag, Daniel (Author) , Toedt, Grischa (Author) , Wittmann, Andrea (Author) , Schöttler, Anna (Author) , Bueren, André von (Author) , Deimling, Andreas von (Author) , Rutkowski, Stefan (Author) , Scheurlen, Wolfram (Author) , Kulozik, Andreas (Author) , Taylor, Michael D. (Author) , Lichter, Peter (Author) , Pfister, Stefan (Author)
Format: Article (Journal)
Language:English
Published: September 12, 2011
In: Journal of clinical oncology
Year: 2011, Volume: 29, Issue: 29, Pages: 3852-3861
ISSN:1527-7755
DOI:10.1200/JCO.2011.36.2798
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1200/JCO.2011.36.2798
Verlag, lizenzpflichtig, Volltext: https://ascopubs.org/doi/10.1200/JCO.2011.36.2798
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Author Notes:Marc Remke, Thomas Hielscher, Andrey Korshunov, Paul A. Northcott, Sebastian Bender, Marcel Kool, Frank Westermann, Axel Benner, Huriye Cin, Marina Ryzhova, Dominik Sturm, Hendrik Witt, Daniel Haag, Grischa Toedt, Andrea Wittmann, Anna Schöttler, André O. von Bueren, Andreas von Deimling, Stefan Rutkowski, Wolfram Scheurlen, Andreas E. Kulozik, Michael D. Taylor, Peter Lichter, and Stefan M. Pfister
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LGR5 is a marker of poor prognosis in glioblastoma and is required for survival of brain cancer stem-like cells by Nakata, Susumu (Author) , Campos, Benito (Author) , Bageritz, Josephine (Author) , Lorenzo Bermejo, Justo (Author) , Becker, Natalia (Author) , Engel, Felix (Author) , Acker, Till (Author) , Momma, Stefan (Author) , Herold-Mende, Christel (Author) , Lichter, Peter (Author) , Radlwimmer, Bernhard (Author) , Goidts, Violaine (Author) ,


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