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Impaired hepatic mitochondrial capacity in nonalcoholic steatohepatitis associated with Type 2 diabetes

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Individuals with type 2 diabetes are at higher risk of progression of nonalcoholic fatty liver (steatosis) to steatohepatitis (NASH), fibrosis, and cirrhosis. The hepatic metabolism of obese individuals adapts by upregulation of mitochondrial capacity, which may be lost during the progression of ste...

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Main Authors: Gancheva, Sofiya (Author) , Kahl, Sabine (Author) , Pesta, Dominik (Author) , Mastrototaro, Lucia (Author) , Dewidar, Bedair (Author) , Strassburger, Klaus (Author) , Sabah, Ehsan (Author) , Esposito, Irene (Author) , Weiß, Jürgen (Author) , Sarabhai, Theresia (Author) , Wolkersdorfer, Martin (Author) , Fleming, Thomas (Author) , Nawroth, Peter Paul (Author) , Zimmermann, Marcel (Author) , Reichert, Andreas S. (Author) , Schlensak, Matthias (Author) , Roden, Michael (Author)
Format: Article (Journal)
Language:English
Published: February 03 2022
In: Diabetes care
Year: 2022, Volume: 45, Issue: 4, Pages: 928-937
ISSN:1935-5548
DOI:10.2337/dc21-1758
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.2337/dc21-1758
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Author Notes:Sofiya Gancheva, Sabine Kahl, Dominik Pesta, Lucia Mastrototaro, Bedair Dewidar, Klaus Strassburger, Ehsan Sabah, Irene Esposito, Jürgen Weiß, Theresia Sarabhai, Martin Wolkersdorfer, Thomas Fleming, Peter Nawroth, Marcel Zimmermann, Andreas S. Reichert, Matthias Schlensak and Michael Roden
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The role of exosomes for sustained specific cardiorespiratory and metabolic improvements in males with type 2 diabetes after detraining by Mastrototaro, Lucia (Author) , Apostolopoulou, Maria (Author) , Hartwig, Sonja (Author) , Strassburger, Klaus (Author) , Lipaeva, Polina (Author) , Trinks, Nina (Author) , Karusheva, Yanislava (Author) , Gancheva, Sofiya (Author) , Trenkamp, Sandra (Author) , Lehr, Stefan (Author) , Al-Hasani, Hadi (Author) , Szendrödi, Julia (Author) , Roden, Michael (Author) ,


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The cardiac autonomic response to acute psychological stress in type 2 diabetes by Monzer, Nelly Lou (Author) , Hartmann, Mechthild (Author) , Buckert, Magdalena (Author) , Wolff, Kira (Author) , Nawroth, Peter Paul (Author) , Kopf, Stefan (Author) , Kender, Zoltán (Author) , Friederich, Hans-Christoph (Author) , Wild, Beate (Author) ,


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Pronounced cortisol response to acute psychosocial stress in type 2 diabetes patients with and without complications by Buckert, Magdalena (Author) , Hartmann, Mechthild (Author) , Monzer, Nelly Lou (Author) , Wolff, Kira (Author) , Nawroth, Peter Paul (Author) , Fleming, Thomas (Author) , Streibel, Carmen (Author) , Henningsen, Nikola (Author) , Wild, Beate (Author) ,


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