Endothelin antagonist as add-on treatment for proteinuria in diabetic nephropathy: is there light at the end of the tunnel?

After the seminal discovery by Yanagisawa et al. [1][1] of the endothelial cell-derived vasopressor endothelin-1 (ET) and eventually the identification of two other isoforms, inhibitors of the ET receptors (ETA, ETB1, and ETB2) were high on the list of therapeutic drugs for the pharmaceutical

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Bibliographic Details
Main Authors: Ritz, Eberhard (Author) , Wenzel, René R. (Author)
Format: Article (Journal)
Language:English
Published: March 31, 2011
In: Journal of the American Society of Nephrology
Year: 2011, Volume: 22, Issue: 4, Pages: 593-595
ISSN:1533-3450
DOI:10.1681/ASN.2011020158
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1681/ASN.2011020158
Verlag, lizenzpflichtig, Volltext: https://jasn.asnjournals.org/content/22/4/593
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Author Notes:Eberhard Ritz and René R. Wenzel

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