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Analysis of EPCAM protein expression in diagnostics of Lynch syndrome

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Purpose: Lynch syndrome is an inherited tumor predisposition syndrome caused by germline mutations of DNA mismatch repair (MMR) genes, mainly MLH1 and MSH2. Recently, germline deletions affecting the epithelial cell adhesion molecule (EPCAM) gene located upstream of MSH2 were identified as a novel m...

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Main Authors: Kloor, Matthias (Author) , Voigt, Anita Yvonne (Author) , Schackert, Hans K. (Author) , Schirmacher, Peter (Author) , Knebel Doeberitz, Magnus von (Author) , Bläker, Hendrik (Author)
Format: Article (Journal)
Language:English
Published: 2011
In: Journal of clinical oncology
Year: 2011, Volume: 29, Issue: 2, Pages: 223-227
ISSN:1527-7755
DOI:10.1200/JCO.2010.32.0820
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1200/JCO.2010.32.0820
Verlag, lizenzpflichtig, Volltext: https://ascopubs.org/doi/10.1200/JCO.2010.32.0820
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Author Notes:Matthias Kloor, Anita Y. Voigt, Hans K. Schackert, Peter Schirmacher, Magnus von Knebel Doeberitz, and Hendrik Bläker
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Analysis of EPCAM protein expression in diagnostics of Lynch syndrome by Kloor, Matthias (Author) , Voigt, Anita Yvonne (Author) , Schackert, Hans K. (Author) , Schirmacher, Peter (Author) , Knebel Doeberitz, Magnus von (Author) , Bläker, Hendrik (Author) ,


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