MUON: multimodal omics analysis framework

Advances in multi-omics have led to an explosion of multimodal datasets to address questions from basic biology to translation. While these data provide novel opportunities for discovery, they also pose management and analysis challenges, thus motivating the development of tailored computational sol...

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Bibliographic Details
Main Authors: Bredikhin, Danila (Author) , Kats, Ilia (Author) , Stegle, Oliver (Author)
Format: Article (Journal)
Language:English
Published: 01 February 2022
In: Genome biology
Year: 2022, Volume: 23, Pages: 1-12
ISSN:1474-760X
DOI:10.1186/s13059-021-02577-8
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13059-021-02577-8
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Author Notes:Danila Bredikhin, Ilia Kats and Oliver Stegle
Description
Summary:Advances in multi-omics have led to an explosion of multimodal datasets to address questions from basic biology to translation. While these data provide novel opportunities for discovery, they also pose management and analysis challenges, thus motivating the development of tailored computational solutions. Here, we present a data standard and an analysis framework for multi-omics, MUON, designed to organise, analyse, visualise, and exchange multimodal data. MUON stores multimodal data in an efficient yet flexible and interoperable data structure. MUON enables a versatile range of analyses, from data preprocessing to flexible multi-omics alignment.
Item Description:Gesehen am 20.09.2022
Physical Description:Online Resource
ISSN:1474-760X
DOI:10.1186/s13059-021-02577-8