MUON: multimodal omics analysis framework

Advances in multi-omics have led to an explosion of multimodal datasets to address questions from basic biology to translation. While these data provide novel opportunities for discovery, they also pose management and analysis challenges, thus motivating the development of tailored computational sol...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Bredikhin, Danila (VerfasserIn) , Kats, Ilia (VerfasserIn) , Stegle, Oliver (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 01 February 2022
In: Genome biology
Year: 2022, Jahrgang: 23, Pages: 1-12
ISSN:1474-760X
DOI:10.1186/s13059-021-02577-8
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13059-021-02577-8
Volltext
Verfasserangaben:Danila Bredikhin, Ilia Kats and Oliver Stegle
Beschreibung
Zusammenfassung:Advances in multi-omics have led to an explosion of multimodal datasets to address questions from basic biology to translation. While these data provide novel opportunities for discovery, they also pose management and analysis challenges, thus motivating the development of tailored computational solutions. Here, we present a data standard and an analysis framework for multi-omics, MUON, designed to organise, analyse, visualise, and exchange multimodal data. MUON stores multimodal data in an efficient yet flexible and interoperable data structure. MUON enables a versatile range of analyses, from data preprocessing to flexible multi-omics alignment.
Beschreibung:Gesehen am 20.09.2022
Beschreibung:Online Resource
ISSN:1474-760X
DOI:10.1186/s13059-021-02577-8