Cep63 recruits Cdk1 to the centrosome: implications for regulation of mitotic entry, centrosome amplification, and genome maintenance

The discovery how Cdk1 kinase is recruited to centrosomes advances understanding of how mitosis is controlled and why centrosome amplification and chromosomal breakage occur so commonly in cancer cells.

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Bibliographic Details
Main Authors:	Löffler, Harald (Author) , Fechter, Anne (Author) , Matuszewska, Marc (Author) , Saffrich, Rainer (Author) , Mistrik, Martin (Author) , Marhold, Joachim (Author) , Hornung, Christin (Author) , Westermann, Frank (Author) , Bartek, Jiri (Author) , Krämer, Alwin (Author)
Format:	Article (Journal)
Language:	English
Published:	2011
In:	Cancer research Year: 2011, Volume: 71, Issue: 6, Pages: 2129-2139
ISSN:	1538-7445
DOI:	10.1158/0008-5472.CAN-10-2684
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1158/0008-5472.CAN-10-2684 Verlag, lizenzpflichtig, Volltext: https://aacrjournals.org/cancerres/article/71/6/2129/570389/Cep63-Recruits-Cdk1-to-the-Centrosome-Implications
Author Notes:	Harald Löffler, Anne Fechter, Marc Matuszewska, Rainer Saffrich, Martin Mistrik, Joachim Marhold, Christin Hornung, Frank Westermann, Jiri Bartek, and Alwin Krämer

Description
Summary:	The discovery how Cdk1 kinase is recruited to centrosomes advances understanding of how mitosis is controlled and why centrosome amplification and chromosomal breakage occur so commonly in cancer cells.
Item Description:	Gesehen am 20.09.2022
Physical Description:	Online Resource
ISSN:	1538-7445
DOI:	10.1158/0008-5472.CAN-10-2684