Cep63 recruits Cdk1 to the centrosome: implications for regulation of mitotic entry, centrosome amplification, and genome maintenance
The discovery how Cdk1 kinase is recruited to centrosomes advances understanding of how mitosis is controlled and why centrosome amplification and chromosomal breakage occur so commonly in cancer cells.
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| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
2011
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| In: |
Cancer research
Year: 2011, Volume: 71, Issue: 6, Pages: 2129-2139 |
| ISSN: | 1538-7445 |
| DOI: | 10.1158/0008-5472.CAN-10-2684 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1158/0008-5472.CAN-10-2684 Verlag, lizenzpflichtig, Volltext: https://aacrjournals.org/cancerres/article/71/6/2129/570389/Cep63-Recruits-Cdk1-to-the-Centrosome-Implications |
| Author Notes: | Harald Löffler, Anne Fechter, Marc Matuszewska, Rainer Saffrich, Martin Mistrik, Joachim Marhold, Christin Hornung, Frank Westermann, Jiri Bartek, and Alwin Krämer |
MARC
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