The need for vigilance in extended criteria donors with a past history of malignancy: a case report and review of literature
BACKGROUND: Organ shortage has prompted many transplant centers to extend their criteria for organ acceptance including the history of a variety of co-morbidities in donors. The use of organs from donors with a past medical history of malignancy in order to reduce the waiting list mortalities remain...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2011.03.22
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| In: |
Annals of transplantation
Year: 2011, Jahrgang: 16, Heft: 1, Pages: 75-79 |
| ISSN: | 1425-9524 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://annalsoftransplantation.com/reprintOrder/index/idArt/881643
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| Verfasserangaben: | Arash Nickkholgh, Erich Frey, Christoph Krenzel, Werner Lauchart, Christa Flechtenmacher, Jan Schmidt, Peter Schemmer |
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| 245 | 1 | 4 | |a The need for vigilance in extended criteria donors with a past history of malignancy |b a case report and review of literature |c Arash Nickkholgh, Erich Frey, Christoph Krenzel, Werner Lauchart, Christa Flechtenmacher, Jan Schmidt, Peter Schemmer |
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| 520 | |a BACKGROUND: Organ shortage has prompted many transplant centers to extend their criteria for organ acceptance including the history of a variety of co-morbidities in donors. The use of organs from donors with a past medical history of malignancy in order to reduce the waiting list mortalities remains a dilemma. - CASE REPORT: Herein we report a 62-year-old female donor with a history of a presumably cured serous adenocarcinoma of the ovary and underscore the need for vigilance in the search of an active site of cancer while assessing these donors for organ recovery. - CONCLUSIONS: In order to minimize the risk of donor tumor transmission, especially in the donors with a past medical history of cancer, extensive evaluation of the donor including the surgical exploration of all body cavities is absolutely necessary. Any suspicious lesion should prompt a frozen section biopsy. In this regard, an on-call pathologist to do the frozen section should be an integral part of the transplant team. | ||
| 650 | 4 | |a Cystadenocarcinoma, Serous | |
| 650 | 4 | |a Donor Selection | |
| 650 | 4 | |a Female | |
| 650 | 4 | |a Humans | |
| 650 | 4 | |a Middle Aged | |
| 650 | 4 | |a Neoplasm Recurrence, Local | |
| 650 | 4 | |a Neoplasms | |
| 650 | 4 | |a Ovarian Neoplasms | |
| 650 | 4 | |a Risk Factors | |
| 650 | 4 | |a Tissue and Organ Harvesting | |
| 650 | 4 | |a Tissue Donors | |
| 650 | 4 | |a Transplants | |
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| 700 | 1 | |a Krenzel, Christoph |e VerfasserIn |4 aut | |
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