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The need for vigilance in extended criteria donors with a past history of malignancy: a case report and review of literature

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BACKGROUND: Organ shortage has prompted many transplant centers to extend their criteria for organ acceptance including the history of a variety of co-morbidities in donors. The use of organs from donors with a past medical history of malignancy in order to reduce the waiting list mortalities remain...

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Hauptverfasser: Nickkholgh, Arash (VerfasserIn) , Frey, Erich (VerfasserIn) , Krenzel, Christoph (VerfasserIn) , Lauchart, Werner (VerfasserIn) , Flechtenmacher, Christa (VerfasserIn) , Schmidt, Jan (VerfasserIn) , Schemmer, Peter (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2011.03.22
In: Annals of transplantation
Year: 2011, Jahrgang: 16, Heft: 1, Pages: 75-79
ISSN:1425-9524
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://annalsoftransplantation.com/reprintOrder/index/idArt/881643
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Verfasserangaben:Arash Nickkholgh, Erich Frey, Christoph Krenzel, Werner Lauchart, Christa Flechtenmacher, Jan Schmidt, Peter Schemmer
Beschreibung
Zusammenfassung:BACKGROUND: Organ shortage has prompted many transplant centers to extend their criteria for organ acceptance including the history of a variety of co-morbidities in donors. The use of organs from donors with a past medical history of malignancy in order to reduce the waiting list mortalities remains a dilemma. - CASE REPORT: Herein we report a 62-year-old female donor with a history of a presumably cured serous adenocarcinoma of the ovary and underscore the need for vigilance in the search of an active site of cancer while assessing these donors for organ recovery. - CONCLUSIONS: In order to minimize the risk of donor tumor transmission, especially in the donors with a past medical history of cancer, extensive evaluation of the donor including the surgical exploration of all body cavities is absolutely necessary. Any suspicious lesion should prompt a frozen section biopsy. In this regard, an on-call pathologist to do the frozen section should be an integral part of the transplant team.
Beschreibung:Gesehen am 22.09.2022
Beschreibung:Online Resource
ISSN:1425-9524

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