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µCT to quantify muco-obstructive lung disease and effects of neutrophil elastase knockout in mice

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Muco-obstructive lung diseases are characterized by airway obstruction and hyperinflation, which can be quantified by imaging. Our aim was to evaluate µCT for longitudinal quantification of muco-obstructive lung disease in β-epithelial Na+ channel overexpressing (Scnn1b-TG) mice and of the effects o...

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Main Authors: Zhu, Lin (Author) , Dürr, Julia (Author) , Zhou-Suckow, Zhe (Author) , Wagner, Willi Linus (Author) , Weinheimer, Oliver (Author) , Salomon, Johanna J. (Author) , Leitz, Dominik (Author) , Konietzke, Philip (Author) , Yu, Hong (Author) , Ackermann, Maximilian (Author) , Stiller, Wolfram (Author) , Kauczor, Hans-Ulrich (Author) , Mall, Marcus A. (Author) , Wielpütz, Mark Oliver (Author)
Format: Article (Journal)
Language:English
Published: January 26, 2022
In: American journal of physiology. Lung cellular and molecular physiology
Year: 2022, Volume: 322, Issue: 3, Pages: L401-L411
ISSN:1522-1504
DOI:10.1152/ajplung.00341.2021
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1152/ajplung.00341.2021
Verlag, lizenzpflichtig, Volltext: https://journals.physiology.org/doi/full/10.1152/ajplung.00341.2021
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Author Notes:Lin Zhu, Julia Duerr, Zhe Zhou-Suckow, Willi Wagner, Oliver Weinheimer, Johanna Salomon, Dominik Leitz, Philip Konietzke, Hong Yu, Maximilian Ackermann, Wolfram Stiller, Hans-Ulrich Kauczor, Marcus A. Mall, Mark O. Wielpütz
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Combination of µCT and light microscopy for generation-specific stereological analysis of pulmonary arterial branches: a proof-of-concept study by Grothausmann, Roman (Author) , Labode, Jonas (Author) , Hernandez-Cerdan, Pablo (Author) , Haberthür, David (Author) , Hlushchuk, Ruslan (Author) , Lobachev, Oleg (Author) , Brandenberger, Christina (Author) , Gie, Andre George (Author) , Salaets, Thomas (Author) , Toelen, Jaan (Author) , Wagner, Willi Linus (Author) , Mühlfeld, Christian Axel (Author) ,


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