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Transcriptomic analysis of resistance and short-term induction response to pyrethroids, in Anopheles coluzzii legs

Insecticide-treated bed nets and indoor residual spraying comprise the major control measures against Anopheles gambiae sl, the dominant vector in sub-Saharan Africa. The primary site of contact with insecticide is through the mosquitoes’ legs, which represents the first barrier insecticides have to...

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Hauptverfasser: Kefi, Mary (VerfasserIn) , Charamis, J. (VerfasserIn) , Balabanidou, V. (VerfasserIn) , Ioannidis, P. (VerfasserIn) , Ranson, H. (VerfasserIn) , Ingham, Victoria (VerfasserIn) , Vontas, J. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 13 December 2021
In: BMC genomics
Year: 2021, Jahrgang: 22, Pages: 1-17
ISSN:1471-2164
DOI:10.1186/s12864-021-08205-w
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12864-021-08205-w
Volltext
Verfasserangaben:M. Kefi, J. Charamis, V. Balabanidou, P. Ioannidis, H. Ranson, V.A. Ingham and J. Vontas
Beschreibung
Zusammenfassung:Insecticide-treated bed nets and indoor residual spraying comprise the major control measures against Anopheles gambiae sl, the dominant vector in sub-Saharan Africa. The primary site of contact with insecticide is through the mosquitoes’ legs, which represents the first barrier insecticides have to bypass to reach their neuronal targets. Proteomic changes and leg cuticle modifications have been associated with insecticide resistance that may reduce the rate of penetration of insecticides. Here, we performed a multiple transcriptomic analyses focusing on An. coluzzii legs.
Beschreibung:Gesehen am 04.10.2022
Beschreibung:Online Resource
ISSN:1471-2164
DOI:10.1186/s12864-021-08205-w

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