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Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by iron regulatory proteins

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Iron regulatory proteins (IRPs) 1 and 2 are RNA-binding proteins that control cellular iron metabolism by binding to conserved RNA motifs called iron-responsive elements (IREs). The currently known IRP-binding mRNAs encode proteins involved in iron uptake, storage, and release as well as heme synthe...

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Main Authors: Sanchez, Mayka (Author) , Galy, Bruno (Author) , Schwanhaeusser, Bjoern (Author) , Blake, Jonathon (Author) , Bähr-Ivacevic, Tomi (Author) , Benes, Vladimir (Author) , Selbach, Matthias (Author) , Muckenthaler, Martina (Author) , Hentze, Matthias W. (Author)
Format: Article (Journal)
Language:English
Published: September 22, 2011
In: Blood
Year: 2011, Volume: 118, Issue: 22, Pages: e168-e179
ISSN:1528-0020
DOI:10.1182/blood-2011-04-343541
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1182/blood-2011-04-343541
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Author Notes:Mayka Sanchez, Bruno Galy, Bjoern Schwanhaeusser, Jonathon Blake, Tomi Bähr-Ivacevic, Vladimir Benes, Matthias Selbach, Martina U. Muckenthaler, and Matthias W. Hentze
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Mycobacteria-induced anaemia revisited: a molecular approach reveals the involvement of NRAMP1 and lipocalin-2, but not of hepcidin by Rodrigues, Pedro N. S. (Author) , Gomes, Sandro S. (Author) , Neves, João V. (Author) , Gomes-Pereira, Sandra (Author) , Correia-Neves, Margarida (Author) , Nunes-Alves, Cláudio (Author) , Stolte, Jens (Author) , Sanchez, Mayka (Author) , Appelberg, Rui (Author) , Muckenthaler, Martina (Author) , Gomes, M. Salomé (Author) ,


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