Familial occurrence of systemic vasculitis and rapidly progressive glomerulonephritis
Two familial clusters of systemic vasculitis are described. In one family, microscopic polyangiitis and rapidly progressive glomerulonephritis occurred in HLA-identical siblings; in the second family, 3 second- and fourth-degree related members were affected by Wegener's granulomatosis. Publish...
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| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
1999
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| In: |
American journal of kidney diseases
Year: 1999, Jahrgang: 34, Heft: 2, Pages: 364-373 |
| ISSN: | 1523-6838 |
| DOI: | 10.1016/s0272-6386(99)70371-9 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/s0272-6386(99)70371-9 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/abs/pii/S0272638699703719 
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| Verfasserangaben: | R. Nowack, H. Lehmann, L.F. Flores-Suárez, A. Nanhou, F.J. van der Woude |
| Zusammenfassung: | Two familial clusters of systemic vasculitis are described. In one family, microscopic polyangiitis and rapidly progressive glomerulonephritis occurred in HLA-identical siblings; in the second family, 3 second- and fourth-degree related members were affected by Wegener's granulomatosis. Published clusters of systemic vasculitides and Goodpasture's syndrome are reviewed, and, together with the observed families, the evidence for genetic susceptibility and a causative role of environmental factors for these diseases with special emphasis on the HLA system is discussed. |
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| Beschreibung: | Gesehen am 05.10.2022 |
| Beschreibung: | Online Resource |
| ISSN: | 1523-6838 |
| DOI: | 10.1016/s0272-6386(99)70371-9 |