Severe dysfunction of respiratory chain and cholesterol metabolism in Atp7b−/− mice as a model for Wilson disease

Wilson disease (WD) is caused by mutations of the WD gene ATP7B resulting in copper accumulation in different tissues. WD patients display hepatic and neurological disease with yet poorly understood pathomechanisms. Therefore, we studied age-dependent (3, 6, 47weeks) biochemical and bioenergetical c...

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Main Authors:	Sauer, Sven (Author) , Merle, Uta (Author) , Opp, Silvana (Author) , Haas, Dorothea (Author) , Hoffmann, Georg F. (Author) , Stremmel, Wolfgang (Author) , Okun, Jürgen G. (Author)
Format:	Article (Journal)
Language:	English
Published:	2 September 2011
In:	Biochimica et biophysica acta. Molecular basis of disease Year: 2011, Volume: 1812, Issue: 12, Pages: 1607-1615
ISSN:	1879-260X
DOI:	10.1016/j.bbadis.2011.08.011
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.bbadis.2011.08.011 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0925443911001931
Author Notes:	Sven W. Sauer, Uta Merle, Silvana Opp, Dorothea Haas, Georg F. Hoffmann, Wolfgang Stremmel, Jürgen G. Okun

Metallothionein is elevated in liver and duodenum of Atp7b(−/−) mice by Zhang-Hagenlocher, Christine (Author) , Volkmann, Martin (Author) , Tuma-Kellner, Sabine (Author) , Stremmel, Wolfgang (Author) , Merle, Uta (Author) ,

in: BioMetals, 31 (2018), 4, Seite 617-625

Verlag, lizenzpflichtig, Volltext

Article (Journal) Online Resource

Severe dysfunction of respiratory chain and cholesterol metabolism in Atp7b−/− mice as a model for Wilson disease

Metallothionein is elevated in liver and duodenum of Atp7b(−/−) mice by Zhang-Hagenlocher, Christine (Author) , Volkmann, Martin (Author) , Tuma-Kellner, Sabine (Author) , Stremmel, Wolfgang (Author) , Merle, Uta (Author) ,

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