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Association of the VEGF 936C>T polymorphism with FDG uptake, clinical, histopathological, and metabolic response in patients with adenocarcinomas of the esophagogastric junction

The MUNICON trial confirmed prospectively the usefulness of early response evaluation by 2-deoxy-2-[F-18]fluoro-D-glucose-positron emission tomography (FDG-PET) . Metabolic responders (R) showed initially a higher FDG uptake compared with nonresponders (p = 0.018). An association of the vascular end...

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Hauptverfasser: Lorenzen, Sylvie (VerfasserIn) , Panzram, Benjamin (VerfasserIn) , Keller, Gisela (VerfasserIn) , Lordick, Florian (VerfasserIn) , Herrmann, Ken (VerfasserIn) , Becker, Karin (VerfasserIn) , Langer, Ruppert (VerfasserIn) , Schwaiger, Markus (VerfasserIn) , Siewert, Jorg Rudiger (VerfasserIn) , Ott, Katja (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 2011
In: Molecular imaging & biology
Year: 2011, Jahrgang: 13, Pages: 178-186
ISSN:1860-2002
DOI:10.1007/s11307-010-0330-0
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s11307-010-0330-0
Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s11307-010-0330-0
Volltext
Verfasserangaben:Sylvie Lorenzen, Ben Panzram, Gisela Keller, Florian Lordick, Ken Herrmann, Karin Becker, Ruppert Langer, Markus Schwaiger, Jorg Rudiger Siewert, Katja Ott
Beschreibung
Zusammenfassung:The MUNICON trial confirmed prospectively the usefulness of early response evaluation by 2-deoxy-2-[F-18]fluoro-D-glucose-positron emission tomography (FDG-PET) . Metabolic responders (R) showed initially a higher FDG uptake compared with nonresponders (p = 0.018). An association of the vascular endothelial growth factor (VEGF) 936C>T polymorphism and FDG uptake was reported for breast cancer. Therefore, we investigated the VEGF 936C>T polymorphism for an association with response and survival.
Beschreibung:Published online: 7 May 2010
Gesehen am 10.10.2022
Beschreibung:Online Resource
ISSN:1860-2002
DOI:10.1007/s11307-010-0330-0

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