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Telomerase subunit Est2 marks internal sites that are prone to accumulate DNA damage

The main function of telomerase is at the telomeres but under adverse conditions telomerase can bind to internal regions causing deleterious effects as observed in cancer cells.

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Bibliographische Detailangaben
Hauptverfasser: Pandey, Satyaprakash (VerfasserIn) , Hajikazemi, Mona (VerfasserIn) , Zacheja, Theresa (VerfasserIn) , Schalbetter, Stephanie (VerfasserIn) , Neale, Matthew J. (VerfasserIn) , Baxter, Jonathan (VerfasserIn) , Guryev, Victor (VerfasserIn) , Hofmann, Andreas (VerfasserIn) , Heermann, Dieter W. (VerfasserIn) , Juranek, Stefan A. (VerfasserIn) , Paeschke, Katrin (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 20 November 2021
In: BMC biology
Year: 2021, Jahrgang: 19, Pages: 1-15
ISSN:1741-7007
DOI:10.1186/s12915-021-01167-1
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12915-021-01167-1
Volltext
Verfasserangaben:Satyaprakash Pandey, Mona Hajikazemi, Theresa Zacheja, Stephanie Schalbetter, Matthew J. Neale, Jonathan Baxter, Victor Guryev, Andreas Hofmann, Dieter W. Heermann, Stefan A. Juranek and Katrin Paeschke

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650 4 |a Genome stability 
650 4 |a Telomerase 
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