HIV-1 Vpu blocks recycling and biosynthetic transport of the intrinsic immunity factor CD317/tetherin to overcome the virion release restriction
The intrinsic immunity factor CD317 (BST-2/HM1.24/tetherin) imposes a barrier to HIV-1 release at the cell surface that can be overcome by the viral protein Vpu. Expression of Vpu results in a reduction of CD317 surface levels; however, the mechanism of this Vpu activity and its contribution to the...
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| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
May 24, 2011
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| In: |
mBio
Year: 2011, Jahrgang: 2, Heft: 3, Pages: 1-13 |
| ISSN: | 2150-7511 |
| DOI: | 10.1128/mBio.00036-11 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1128/mBio.00036-11 Verlag, lizenzpflichtig, Volltext: https://journals.asm.org/doi/10.1128/mBio.00036-11 
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| Verfasserangaben: | Sarah Schmidt, Joëlle V. Fritz, Julia Bitzegeio, Oliver T. Fackler, Oliver T. Keppler |
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