HIV-1 Vpu blocks recycling and biosynthetic transport of the intrinsic immunity factor CD317/tetherin to overcome the virion release restriction

The intrinsic immunity factor CD317 (BST-2/HM1.24/tetherin) imposes a barrier to HIV-1 release at the cell surface that can be overcome by the viral protein Vpu. Expression of Vpu results in a reduction of CD317 surface levels; however, the mechanism of this Vpu activity and its contribution to the...

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Bibliographic Details
Main Authors:	Schmidt, Sarah (Author) , Fritz, Joëlle (Author) , Bitzegeio, Julia (Author) , Fackler, Oliver Till (Author) , Keppler, Oliver Till (Author)
Format:	Article (Journal)
Language:	English
Published:	May 24, 2011
In:	mBio Year: 2011, Volume: 2, Issue: 3, Pages: 1-13
ISSN:	2150-7511
DOI:	10.1128/mBio.00036-11
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1128/mBio.00036-11 Verlag, lizenzpflichtig, Volltext: https://journals.asm.org/doi/10.1128/mBio.00036-11
Author Notes:	Sarah Schmidt, Joëlle V. Fritz, Julia Bitzegeio, Oliver T. Fackler, Oliver T. Keppler

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HIV-1 Vpu blocks recycling and biosynthetic transport of the intrinsic immunity factor CD317/tetherin to overcome the virion release restriction

The pathogenicity factor Nef in HIV-1 infection by Obermaier, Benedikt (Author)

HIV-1 Nef interferes with T-lymphocyte circulation through confined environments in vivo by Stolp-Rastätter, Bettina (Author) , Imle, Andrea (Author) , Fackler, Oliver Till (Author) ,

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