How HIV takes advantage of the cytoskeleton in entry and replication
The host cell cytoskeleton plays a key role in the life cycle of viral pathogens whose propagation depends on mandatory intracellular steps. Accordingly, also the human immunodeficiency virus type 1 (HIV-1) has evolved strategies to exploit and modulate in particular the actin cytoskeleton for its p...
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| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
28 March 2011
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| In: |
Viruses
Year: 2011, Jahrgang: 3, Heft: 4, Pages: 293-311 |
| ISSN: | 1999-4915 |
| DOI: | 10.3390/v3040293 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/v3040293 Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/1999-4915/3/4/293 
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| Verfasserangaben: | Bettina Stolp and Oliver T. Fackler |
| Zusammenfassung: | The host cell cytoskeleton plays a key role in the life cycle of viral pathogens whose propagation depends on mandatory intracellular steps. Accordingly, also the human immunodeficiency virus type 1 (HIV-1) has evolved strategies to exploit and modulate in particular the actin cytoskeleton for its purposes. This review will recapitulate recent findings on how HIV-1 hijacks the cytoskeleton to facilitate entry into, transport within and egress from host cells as well as to commandeer communication of infected with uninfected bystander cells. |
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| Beschreibung: | Gesehen am 24.10.2022 |
| Beschreibung: | Online Resource |
| ISSN: | 1999-4915 |
| DOI: | 10.3390/v3040293 |