Autoantibodies as predictors for clinical outcome and toxicity for immunotherapy

Peripheral blood autoantibody signatures might be useful biomarkers of immunotherapy outcome. Signatures predicting melanoma recurrence and toxicity during adjuvant immunotherapy were recently presented. Whether autoantibodies are bystanders or have a pathophysiologic role is unknown, and further ef...

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Bibliographic Details
Main Authors: Hassel, Jessica C. (Author) , Luke, Jason (Author)
Format: Article (Journal)
Language:English
Published: September 15, 2022
In: Clinical cancer research
Year: 2022, Volume: 28, Issue: 18, Pages: 3914-3916
ISSN:1557-3265
DOI:10.1158/1078-0432.CCR-22-1664
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1158/1078-0432.CCR-22-1664
Verlag, lizenzpflichtig, Volltext: https://aacrjournals.org/clincancerres/article/28/18/3914/708989/Autoantibodies-as-Predictors-for-Clinical-Outcome
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Author Notes:Jessica C. Hassel and Jason J. Luke
Description
Summary:Peripheral blood autoantibody signatures might be useful biomarkers of immunotherapy outcome. Signatures predicting melanoma recurrence and toxicity during adjuvant immunotherapy were recently presented. Whether autoantibodies are bystanders or have a pathophysiologic role is unknown, and further efforts are needed to investigate potential mechanisms and determine causation.See related article by Johannet et al., p. 4121
Item Description:Gesehen am 25.10.2022
Physical Description:Online Resource
ISSN:1557-3265
DOI:10.1158/1078-0432.CCR-22-1664